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In recent years there has been a clear rise in scientific collaboration, as well as in studies on the subject. While most scholars examine disciplines traditionally known to be collaborative, such as physics and space research, this book focuses on biology. It investigates the growing collaboration in the life sciences, or the emergence of what is called 'big biology'. While the Human Genome Project is often presented as the first large-scale research project in biology, cooperation in the life sciences has a longer history. A comparison between centralised 'big physics' and 'big biology' reveals how the latter has a networked structure, which evolved in interaction with the integration of information and communication technologies. By concentrating on the construction of these networks, three contemporary large-scale research collaborations are analysed: the Census of Marine Life that aims to make an inventory of life in the oceans, the Silicon Cell initiative that wants to design a replica of a cell in a computer, and the VIRGO consortium, which investigates host-virus interaction to develop a new therapy against influenza. This book demonstrates how the process of making science bigger, or the 'supersizing of science', transforms the ways in which science is organised while it also changes the work of scientists involved. As such, this has both scholarly and professional implications for the next generation of scientists. ... Read more

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Nottingham University, U.K.Reviews and discussions of the most current sequence analysis software packages for both desktop and mainframe machines. Chapters are arranged by function. For researchers. 15 contributors, 8 U.S. DNLM: Sequence analysis--methods. ... Read more

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The papers assembled in this volume bring the reader to the forefront of research on the third component of complement, one of the most versatile and multifunctional molecules known to date. Unlike publications on individual characteristics, this vollume brings together all the structural and functional aspects of C3 and the C3-binding proteins, the latter including serum proteins, cell surface receptors and proteins of foreign origin. A wealth of information on the various aspects of the genetics, chemistry, biology and pathophysiology of C3 and of the 20 different proteins described to date to react with C3 is presented in numerous concise and comprehensive reviews. ... Read more

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This special issue of the Advances in Experimental Medicine and Biology presents much of the research described at the recent 2nd International Tissue Engineering Conference held in Crete in May 2005. The conference brought together over 150 researchers from around the world to examine the emerging and most advanced aspects of their particular field. The chapters reflect a diverse group of authors, including both clinicians and academicians.

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The proliferation of extracellular matrix family members reflects the progress in cloning techniques in recent years. PCR, in particular, has made a tremendous difference. These technical advances are covered in this volume. ... Read more

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In Situ Hybridization: A Practical Approach is a comprehensive practical guide with step-by-step laboratory protocols for the preparation of cloned DNA, RNA, and oligonucleotide probes (with both radioactive and non-radioactive labels) and their hybridization to mRNA, viral DNA, and chromosomal DNA. Methods are provided for the analysis of cells, tissue sections, and whole embryos. In addition, techniques are presented for carrying out in situ hybridization in combination with the immunochemical detection of protein, and for using it at the electron microscopic level. This detailed work is essential for any researcher wishing to master the widespread applications of this important biotechnology. ... Read more

Customer Reviews (1)

Exellent and newest protocol
This book gives newest and exellent protocol. Contents are not so big but enough detail to follow experiments. ... Read more

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Tissue Engineering, Second Edition, provides a comprehensive volume that integrates a wide spectrum of methods required to implement current and future progress in tissue engineering. Leading experts in various disciplines provide examples of recent advances in tissue engineering-related methodologies. Authors present authoritative discussions on topics including in vitro expansion of tissue cells by conditional proliferation; stem cell engineering using transducible Cre recombinase; skeletal stem cells for tissue engineering; synthetic hydrogel matrices for guided bladder tissue regeneration; artificial skin; artificial pancreas; cardiomyocytes from human and mouse embryonic stem cells; and biological scaffolds for heart valve tissue engineering.

Tissue Engineering, Second Edition, supplies an understanding of diverse technologies and methods used to drive tissue engineering into a clinical reality. The knowledge contained in this volume represents the impressive progress made in the decade that tissue engineering has rapidly evolved.

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If you wish to grow or characterize embryonic stem cells or persuade them to differentiate into a particular cell type, then this book contains information that is vital to your success. The aim is to provide clear simple instructions and protocols for growing, maintaining and characterizing embryonic stem cells and details of the various methods used to make stem cells differentiate into specific cell types. The contents will be of interest to stem cell biologists, tissue engineers and scientists wishing to use embryonic stem cells for therapeutic purposes. Each chapter has been written and edited by internationally respected scientists working at the cutting edge of technological developments in human embryonic stem cells.

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Flow cytometry forms an integral part of both basic biological research and clinical diagnosis in pathology. This straightforward new volume provides a clear, easy-to-read, and practical manual for both clinicians and non-clinicians at all levels of their careers.

The chapter topics range from basic principles to more advanced subjects, such as apoptosis and cell sorting. The book charts the history, development and basic principles of flow cytometry.

Customer Reviews (1)

Cytometry Tips
It's a very good produc; very practical and motivating when reading. I only sugest improve the relation between text and some figures. ... Read more

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Studies of synthetic and biological calcium phosphates (Ca-Ps) improve our understanding of dental calculus, dental caries and the biological fate of Ca-P biomaterials used as bone grafts. This monograph provides an overview of the preparation and physicochemical characterization of Ca-Ps, their transformation or interconversions in vitro and their biological occurrences. The effect of elements like fluoride, carbonate, magnesium, strontium and zinc on the formation and stability of apatites and related Ca-Ps are presented in detail, and new information on factors promoting and inhibiting the formation of Ca-Ps and calcium fluoride is given. ... Read more

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Previous Edition 9780763701925 ... Read more

Customer Reviews (9)

Good INTRODUCTION; not for in-depth study
This book is a good INTRO for undergrads who are interested in VERY GENERAL aspects of Electron Microscopy, but if you're starting your grad studies on the subject, or really want to learn the different techniques it is really not useful.

If you're interested in biological techniques for electron microscopy, the best and most in-depth book available on the subject is M.A. Hayat's Principles and Techniques in Electron Microscopy, which is very detailed (the 2000 edition is unavailable, but you can buy the 1993 edition or read the newest one on google books).

However, if your subject of interest are the physical principles of the electron microscope (and you are a biologist), although a bit old, Sjöstrand's book Electron Microscopy of Cells and Tissues is a very good reference, as well as Wischnitzer's Introduction to Electron Microscopy and Meek's Practical Electron Microscopy for Biologists.

Excellent book
This book is really excellent for beginners to learn electron microscopy because it offers a large and detailed overview on history and techniques used on transmission and scanning electron microscopy.

On the other hand, experts will prefer a more detailed one.

Good book to start with
This book is very good for biologists who start to learn EM techniques. It covers all of the important aspects of electron microscopy for biologists, including theory of scanning and transmission, specimen preparation, digital imaging and image analysis, laboratory safety and interpretation of images.

Perfect!
The book is really brand new with fine pressing. I appreciate your sending very much!

Was not bad on shipping time, but NOT NEW as listed.
I must give credit to the seller for great packaging and timely shipping. Although, the item was specified as being a brand NEW text book. When in fact it had scuff marks and dinges all around the cover and insides, but still in descent condition. The price I feel should have been lower for the item. ... Read more

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Clemson, Univ., SC. Discusses the area of tissue engineering and research on the behavior of biomaterials in clinical settings. Presents clinical data on the use of metal concentration determinations in human serum and urine as indicators of in vivo device performance. For clinicians and researchers. Expanded-outline format. Date of previous edition not cited. ... Read more

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Univ. of South Florida, Tampa. Provides reviews of critical aspects of the subject, including the history, current state, and future implications of work using electric fields to deliver molecules in vivo. Also focuses on protocols used for the delivery of molecules into cells and through the skin. ... Read more