Product Description
Huntington's Disease (HD) is a hereditary illness passed on via a defective gene. There is a fifty per cent chance of inheriting it from a parent and there is yet no cure. "Learning to Live with Huntington's Disease" is one family's poignant story of coping with the symptoms, the diagnosis and the effects of HD. This book presents the struggles and strengths of the whole family when one member loses their future to a terminal illness. Told by the sufferer and other significant family members, the individuals describe the burden of watching yourself and others for symptoms of HD, including involuntary movements, depression, clumsiness, weight loss, slurred speech and sometimes violent tendencies. The family recounts the challenge to remain united and describes how they approached issues such as whether or not to be tested for HD, how much information to disclose to relatives, whether to have children or not and guilt if one sibling inherits the illness and one does not. Both honest and positive, the author stresses the importance of re-inventing yourself and your present, prioritising relationships and retaining a sense of humour. ... Read more

Customer Reviews (3)

The Emotional Side of HD
This short book is a very poignant insight into how HD affects every member of a family.Most of the family members are not writers by profession, but you can't criticize them for speaking from their hearts.It's a devastating story to tell, and we should all be grateful that people like the Sulaimans are willing to share it.But in the end, it's important to know that this book is not a medical text and describes but one family's struggle.If you are looking for a more informative, well-rounded explanation, or if you want to know the cold, hard facts (such as physical symptoms, disease progression, prognosis, etc.), then this book is not a great starting point.

As I have said in other reviews, the body of knowledge on HD is nearly nonexistent.Oliver Quarrell's book, Huntington's Disease (The Facts), is probably the most concise introduction, and the few books authored by and about the Wexler family offer an interesting historical and personal perspective (Mapping Fate: A Memoir of Family, Risk, and Genetic Research; The Woman Who Walked into the Sea: Huntington's and the Making of a Genetic Disease; and Gene Hunter: The Story of Neuropsychologist Nancy Wexler (Women's Adventures in Science), which, although written for young adults, is advanced enough for grown-up readers as well).And of course, the consummate resource for the latest medical information on HD remains the Huntington's Disease Lighthouse, an indispensable website to which Amazon refuses to let me post a link.

Amazing
My mother has huntingtons before i read this book i had nothing to compare my life too i didnt know if the stages that my mother was going through were normal or not but after reading this book i finally have someone to relate too!

A book for all involved who live with Huntington's Disease!
So many people have written rave reviews to the Sulaiman's and the publisher on this book, I was surprised not to see any posted under Amazon's book review!

Huntington's Disease has been so intricately entwined into the fabric of my life since the early 1980's when my only child, Kelly, was diagnosed with the Juvenile form of this devastating disease.Throughout Kelly's life, and since her death at age 30 to complications of JHD in 1998, I have been deeply involved in trying to help families living with Huntington's Disease by providing resources and support where I can."Learning to Live With Huntington's Disease: One Family's Story" is one of the best non-fictional books on HD to be written since Carman Leal's "Faces of Huntington's" was published in 1998!Whether you are a professional involved in providing support to HD families, a person diagnosed with HD, a young person growing up in an HD family, a person at-risk for inheriting the disease, a friend or a relative of a family living with HD, or a spouse thrown into the role of a "caregiver" in an HD family, each chapter in this book not only will touch your heart but will provide you with insight on how this disease affects every single aspect of the life of anyone who is living with HD!

I highly recommend reading "Learning to Live With Huntington's Disease: One Family's Story"!

Jean E. Miller
HD Patient Outreach
HDSA HD CoE at USF~Tampa, FL.
HD Links: http://get-me.to/hdlinks ... Read more

Product Description
Huntington's disease is a genetically inherited condition which results in severe nerve-cell damage in the brain. The hereditary and debilitative nature of the disease means that many people are involved either directly or indirectly by this condition. The recent identification of the faulty gene involved has made the diagnosis of this condition simpler. The majority of people develop the disease between the ages of 35 and 55 years, so for those aware of their genetic risk there are dilemmas to consider - should you have a test to see if you have the gene?Should you start a family?

The new edition of this successful book specifically designed for families of patients with Huntington's disease has been expanded to include a number of important new developments in research and clinical practice that have occurred in the field in recent years. While there are no drugs currently available that slow down or reverse the neurodegenerative process in Huntington's Disease, there is growing data on the use of existing treatments to manage movement disorder, irritability and depression associated with the condition, which are covered here. This edition also includes completely new chapters covering juvenile Huntington's disease and late-stage Huntington's disease, and a fully updated Appendix of relevant patients' organizations. ... Read more

Product Description
Huntington's Disease is a genetically inherited condition, the result of severe nerve-cell damage in the brain. Due to the recent identification of the gene involved, and the debilitating nature of the disease, a great many more people are now affected either directly or indirectly (families and carers) by this condition. The majority of people develop the disease between the ages of 35 and 55, so for those that are aware of a genetic inheritance, there are enormous problems to confront - should you carry on life as normal? Should you start a family? In this, the first book on Huntington's disease written for sufferers and their families, advice is given on living with this disabling illness. Written as much for carers as for the patients themselves, the book aims to answer some of the questions that both sufferer and carer might have. With the identification of the responsible gene, genetic counselling is now available for those at risk of developing the disease. Though some may wish not to use these services, the book clearly explains the role of the counsellor, and what help is additionally available from the various patient organisations worldwide. ... Read more

Product Description

In 1993, the genetic mutation responsible for Huntington’s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that seem to result directly from the expression of the mutant huntingtin gene.

Neurobiology of Huntington’s Disease: Applications to Drug Discovery presents a thorough review of the issues surrounding drug discovery and development for the treatment of this paradigmatic neurodegenerative disease. Drawing on the expertise of key researchers in the field, the book discusses the basic neurobiology of Huntington’s disease and how its monogenic nature confers enormous practical advantages for translational research, including the creation of robust experimental tools, models, and assays to facilitate discovery and validation of molecular targets and drug candidates for HD. Written to support future basic research as well as drug development efforts, this volume:

• Covers the latest research approaches in genetics, genomics, and proteomics, including high-throughput and high-content screening
• Highlights advances in the discovery and development of new drug therapies for neurodegenerative disorders
• Examines the practical realities of preclinical testing, clinical testing strategies, and, ultimately, clinical usage

While the development of effective drug treatments for Huntington's disease continues to be tremendously challenging, a highly interactive and cooperative community of researchers and clinical investigators now brings us to the threshold of potential breakthroughs in the quest for therapeutic agents. The impressive array of drug discovery resources outlined in the text holds much promise for treating this devastating disease, providing hope to long-suffering Huntington’s disease patients and their families.

Product Description
Faces of Huntington's is an incredible collection ofstories, essays, poems, and quotes of those who are in some wayconnected to Huntington's Disease.

The book focuses on over sixty people who have HD, are at risk,caregivers, other family members, adn friends. It is a beacon of lightin what is often a dark world.

30,000 Americans have this terminal neurological disorder. Anadditional 150,000 are at-risk. Somehow, despite the horror ofHuntington's Disease, there is loving support, a positive attitude,and unending hope. There are stories that make you rejoice at theunswerving faith and those that make you cry at the senseless loss.

Faces of Huntington's gives readers a glance at the faces ofheroes. It is guaranteed to bring tears of joy, hope, love andcompassion to your eyes. ... Read more

Customer Reviews (37)

Deeper Appreciation
Leal has done a fantastic job putting faces with a disease that most people know nothing about. She puts the reader right in the midst of the agonizing decisions that people with Huntington's disease have to make.

Since the disease is hereditary, should those with a history of Huntington's in their family get tested for the gene that causes the disease? Should those with the disease have children knowing that they could pass the disease along to the next generation? When, if ever, is it time for the person with the disease to move to a nursing home?

I didn't know anything about Huntington's before I read Leal's book. After reading it, I have a deep appreciation for the struggles that families face after a positive diagnosis.

If you are looking for a book about Huntington's that doesn't gloss over the hard parts of life and yet at the same time shows you what faces of courage, hope and faith can look like during trials, then this book is for you.

If You're Interested in Huntington's, Read This Book.

As a healthcare professional I've worked with a few hundred families touched by HD over the last 17 years. Among those families, this book "Faces..." is known as a tool for hope, support and inspiration. I have purchased many copies of this book over the last few years and given it as a gift to families.
The positive reviews here clearly reflect the overwhelming praise that this book reliably receives from folks touched by HD.
I respect the views of the folks who've posted those negative comments. HD is the worst damn disease that can touch a family and it manifests itself in unlimited ways. And everyone handles it in their own unique way. However, it would be sad ifa family looking for a source of hope like this one turned away from it because of those comments. The overwhelming percentage of folks who've read this book talk about it as an important source of hope and support for themselves.
Read it and see for yourself!

HD
I am in the early stages of HD and I can understand the negative review.My wife has promised me that if my mind becomes that of a four year old, she will not dress me as a four year old and take me to an amusement park and allow strangers to photograph me.I know at that time I might not notice the loss of dignity, but I care now.If we do go, I want to go as an adult with HD, not wearing a "Goofy" shirt. The author seem insensitive to me.

One of the best books I've ever read on the subject
I just re-read Faces of Huntington's and decided it was time to write a review. I am so thankful this book was written and published. Again I was amazed at the author's sensitivity and her ability to pack so much into one book. For far too long there was nothing written about this disease except what was in a medical book. There was certainly nothing about the people themselves. I liked how so many people were included and not just the author. This gave us a much more complete and accurate picture of the disease from all sides.

I was amazed to read the negative review. I understand that not everyone sees the glass half full versus the 99% empty the person who reviewed the book sees. But the review seemed more an attack on the author's character rather than on her work. I feel really sad that someone is so bitter they can't see anything but ugliness no matter where they look. Makes me wonder did they really read the book since in the book I read had stories about suicide, abuse, juvenile Huntington's, death and other real effects of this devastating disease. When I read the review I wondered why this person doesn't write their own book filled with their 42 years of experience.

Faces of Huntington's is one of those books I know I will go back to many times over the years and will recommend to others.

Well written and full of information
I have purchased the book Faces of Huntington's,read it,and recommended it to friends.
This was a book that needed to be written.
For the first time I was able to read stories of other people dealing with this disease,like I am.
It is a book that is very easy to read.
Not all stories are sad , and that was encouraging.
You will find ways to handle your problems by reading how others have.
I found my self re-reading the book many times , its comforting. ... Read more

Product Description
The Test is a memoir of the five years Barema spent in anguish over the decision to take the test for Huntington's disease.Barema recalls his long, emotionally wrought journey from deciding to take the test to receiving the results; he describes how his daily life was consumed by questions and fear; and he movingly depicts the patience of his wife and the compassion of his doctor.The Test is both a suspense story and a vivid portrayal of the devastation Huntington's disease causes the families it strikes. Ultimately, it is a book about the power of hope and love to reach us even in our lowest moments. ... Read more

Customer Reviews (5)

Food for Thought
I read this book in French, so I cannot comment on the translation, but I do disagree with the above comments regarding the content.Anyone who is considering the test for Huntington's Disease should read this book.I found it thought-provoking and worthwhile.

Disjointed and disappointing
My wife has Huntington's Disease and our two sons have this issue to face themselves (whether to take the test that will tell them if they have the rogue gene and will inherit Huntington's Disease, or whether to continue living with uncertainty; with the 50/50 risk of developing the symptoms in their late 30s or 40s). So, I bought The Test to see if there is any insightful thinking in it that could help them. There isn't.

Journalists assume they can write books (the author is a journalist). I know this because I am a journalist and too many of my colleagues assume book-writing is the same skill. It clearly isn't. Also, as no translator is credited at the beginning of the book, I assume Mr. Barema either wrote it in English himself or wrote two versions - one in English and the other in French - on the assumption that his English writing was good enough for the publisher not to get a translator in to do the English version for him (he is French, but spends a lot of time in the USA and studied in the US). Unfortunately, the English is not good enough. It lacks subtlety and, often, clarity. And, as another reviewer has mentioned, below, the facts are too often simply wrong, which is far too casual and thoughtless when the subject matter is so vital for the readers, many of whom will be at risk themselves and will have bought the book for help in dealing with that.

I don't think they will find it, as I don't think it was written to help anyone. It seems to be more of an attempt to turn a personal misfortune into a dramatic work. The material has to be researched and absolutely right so as not to mislead readers who are in the same situation as the author, for whom this is information literally about their own life or death. This book isn't well-researched. Nor is it well structured.

I helped my wife put together her just-published book Learning To Live With Huntington's Disease, and we know how people at risk of this illness need information that has been checked and double-checked to avoid misleading them.

Despite the author's obvious love for his sister and brother, and his horror that they have the disease, there is also a lack of empathy for people with Huntington's in this book that I found shallow. The other people around the author, who are supposed to be central characters to his story, are shadowy and insubstantial and you never get a proper sense of them. You get the feeling the author doesn't either. People with this illness do not have 'nothing in their heads', as Mr. Barema seems to assume sometimes. Nor are they all insane or monstrous, as he says on several occasions. He seems to be over-generalizing from the terrible stories and experiences he had as a child when his mother was dying with Huntington's Disease. Even in the last stages of the illness this is not necessarily always the case. It seems to me his own fear of the illness has led him to play up the cliches.

You can live positively with this illness, even to the last, with enough determination and love.I suspect I am being too harsh. I know my own older son went through several years where he was living a life off the rails, where he was focussed on himself and not on those around him properly. Who can blame him when he had to absorb the information that there was a 50% chance he would not have a future. He pulled through that stage after several years and got himself back together, after we almost lost him.

I feel someone at that stage of the grieving process (this is a process of grieving for your future) who has come through the 'why me?' self-obsessed phase should have written this book to encourage people at risk to realize that yes, it is common to fall apart as your world falls apart around you (which seems to be the stage Mr. Barema was at when writing this book), but that, with love from others AND yourself, you can come thru that stage and become strong again. As Hemingway wrote, the world breaks all of us. But some of us are strong at the broken places. Exactly the same applies to Huntington's Disease. I wish this had been a better book. As it is, I will not be recommending it to my sons as I think it would upset them more than help them.

Warm account of a cold dilemma
The Test is a journalist's first-person account of what it means to live at risk for Huntington's Disease. The everyday experience of hundreds of thousands, it is difficult for most people to imagine, and Jean Berera has done well in humanizing what media usually sell as unimaginable. The difficulties that HD brings to relationships within a family are thoughtfully addressed. I didn't give this book a higher rating because I disapprove of the author's (or editor's) decision not to disclose his gene status until the end of the book, using it as a kind of nonfictional plot device. In my reading, the suspense that this decision inevitably promoted detracted from the author's thoughtful reflections.

Nothing simple about this test...

Aside from the inaccurate statistics in this book, it does serve another purpose.

Barema focuses on the anxiety, emotional turmoil and obsessive behavior that can occur during the test decision making process, which includes mothers/fathers, sisters/brothers, wives/husbands, children, doctors, etc;

Barema also writes about the issues of Huntington's Disease and the overwhelming struggle to live rationally while feeling irrational.

It seems to be a good book for those considering testing for HD and a real effort to educate anyone who may think that taking "The Test" may be as simple as just getting a blood test.

Overshawdowed By Inaccuracy
Couldn't wait to read this book, as my father is struggling with Huntington's Disease, which, of course, meant my own struggle with "to test or not to test."That said, I'm sorry to report that I was sorely disappointed.While I obviously empathize with the subject matter, the inaccuracies in this book drove me nuts and stained this author's credibility with me. Being the journalist that Mr. Barema is I would think an attention to details would be a top priority.Not so, as is evidenced by his bad habit of attributing songs to Woody Guthrie (the most notable public figure with Huntington's) that Woody didn't author."Good Morning America, How Are Ya?" is one.First off, Barema mistitles the song.It's called "The City of New Orleans" and was written by Steve Goodman.It was sung by Arlo Guthrie, NOT Woody."Starry, Starry Night" is another notch inexplicably placed on Woody's song belt.The song was written by Don Mclean.Listen, Mr. Barema, to an author who DID get her facts straight in a book on Bob Dylan, if you're going to make frequent references to a hero like Woody know your game.Also, while the back cover blurb "Huntington's causes death within five to ten years" is gripping and more than likely geared toward sucking in the bookstore browser, it's simply not true.According to every medical web site I've ever haunted since this insidious disease entered our lives (and believe me folks, I've dropped in on them all) death from HD comes within 10-20 years.This is nothing more than an unfortunate and unsettling marketing ploy in my opinion.Apart from facts that fly around like pollen in this memoir, I didn't care for the clipped writing style.Unlike "Publisher's Weekly" it didn't hit me as "moving" or "intense" so much as annoying.Anyway, a real letdown, this one.Save your money and purchase a Woody Guthrie biography instead. ... Read more

Product Description
It is now almost a decade since the identification of the Huntington's Disease gene and its mutation.Major advances in our understanding of the disorder have been made during this time.Since publication of the first two editions, much more extensive evidence exists on how the HD mutation actually causes brain pathology.Experimental tools are now available to take this research further towards new therapeutic approaches. Due to these major changes, this well-established book has been radically updated.An international group of leaders in their particular fields cover the major recent advances in the genetics and neurobiology of the disease. Developments in our understanding of how the molecular basis of the disorder results in brain degeneration, with full coverage of transgenic animal models, neurochemical studies and advances in neuropathology are discussed in detail. The clinical sections cover both neurological and psychiatric aspects as well as new developments in therapy. This book will continue to provide an invaluable source of information for clinicians and scientists involved with Huntington's Disease, including geneticists, psychiatrists and neurologists and basic research workers in genetics and neurobiology. ... Read more

Customer Reviews (1)

Very informative book
This is an excellent, comprehensive book about Huntington's Disease.It is written for doctors, scientists, and other professionals dealing with Huntington's Disease but can also be read by Huntington's Disease families who wish to gain a deeper understanding of the disease. Each chapter is written by experts.There is information about the history of Huntington's Disease, its neuropathology, the psychiatric and behavioral problems, research, genetics, epidemiology, and the treatment of symptoms.

In addition the information about HD that has been published in medical and scientific journals, there is some valuable information from clinical practice that can't be found elsewhere.

I purchased the book to help me answer questions posed by readers of my HD websites and I have found it to be very valuable. ... Read more

Product Description

Customer Reviews (4)

interesting book
This is good book for people with an interest in chorea.The book has some excellent information and fasinating history.However, it does seem like it has been expanded beyond the information the authors have.For example, the story of the women and the sea is told 4-5 times and get repetitive.

rare glimpse
This book is a rare glimpse into the history of a genetic disesase that has been moving to the front and center of genetic research ever since the gene for Huntington's disease was discovered in the early 1990's. This is a dense book, yet I was amazed at the speed with which I read it. Writers and editors must have worked hard to get this distillation of material that enlightens and informs in a way that keeps the reader absorbed and fascinated. I am from an HD family but I think if I were an MD interested in research, or an MD with a highly creative mind or simply a person with a curiosity about genetics as it unfolds in the context of community, this is a stimulating and exciting read.

I expected to be interested, but am astounded, really, at what this book reveals about disease and community. Thank you Alice Wexler and to all those who supported you in this effort. I wish the whole medical community would read your book!

Nancy Hess
Hummelstown, Pennsylvania

A must read for anyone interested in medicine and humanity
Read through the media, and you'll find all sorts of opinions about what diseases deserve more research dollars.Sadly, I can't recall any major media pieces in recent years stressing the need for more focus on Huntington's disease.While it may be a rare condition, there is no illness I can think of that creates more dread in those at risk for developing it and creates more havoc on those who do develop it.Significantly more resources and compassion are needed to fight this illness.

The quick facts:

1)A child born to a parent with Huntington's disease has a 50% chance of developing the illness later in life (if the child inherits a mutant form of the Huntington's gene from his/her parent, he/she has approximately 100% odds of developing the disease later in life).
2)Symptoms of Huntington's disease often develop around age 30 or later--after one has already had children--and late enough in life so that the children can see what happens to their affected parent.
3)Huntington's disease causes an progressive, unrelenting movement disorder (chorea) with progressive mental decline and death.
4)In the past (and no doubt today, too), patients with Huntington's disease and their blood relatives have been stigmitized and ostracized.Within the past century, attempts (some successful) have been made to sterilize patients and prevent them from marrying (in Germany and the US).
5)The disease may be so stigmitizing and physically destructive that children of Huntington's patients who start to develop symptoms are at risk for suicide.In fact, this book is based upon the story of a woman who develops symptoms and literally walks into the sea to end her life.

This book contains an interesting compilation of stories of the doctors who characterized the disease in the United States of America. A few highlights of the book:

The disease had been characterized by others well before George Huntington's major publication in 1872.However, Huntington meticulously demonstrated the autosomal dominant pattern of the disease--with about complete penetrance.At that time in history, perhaps only one form of blindness had been shown to have a similar strict, heritable pattern, but Huntington was unaware of that.Huntington also published his article only a few years after the Austrian Monk Mendel published his study on the heritable traits of peas--but Huntington was unaware of that paper too.

Huntington's disease also goes by the name St. Vitus's dance and "the Magrums."I have no idea where the name "Magrums" comes from--maybe I should reread the book.However, St. Vitus is a patron saint of dancers.Apparantly, epileptic and chorea patients used to pray to St. Vitus to try and cure their diseases.

Doctors used to try and treat Huntington's disease with herbs, medicines such as opium & digitalis, and a healthy diet.

William Osler was very interested in Huntington's disease, and admired Huntington's 1872 paper greatly.He even wrote to Huntington to try and arrange a trip to East Hampton to observe patients. He was initially rebuffed because the patients in East Hampton were extremely sensitive about their illness and didn't want to be observed.

Huntington's patients became a target of the eugenics movement in the 20th century.

GREAT INSIGHT
This book is well written and gives a true insight to Huntington's. This is a book to read even if you are not affected by this illness. ... Read more

Product Description
Huntington's disease, chorea or disorder (HD) is an incurable neurodegenerative genetic disorder, which affects muscle co-ordination and some cognitive functions, typically becoming noticeable in middle age. It is the most common genetic cause of abnormal involuntary writhing movements called chorea and is much more common in people of Western European descent than in those from Asia or Africa. The disease is caused by a dominant mutation on either of the two copies of a gene called Huntington. This book gathers and presents current research in the study of Huntington's Disease including the outlining effects of mutant htt in the nucleus and cytoplasm and the role of cell-cell interactions in Huntington's Disease pathology, as well as a review of the role of Huntington (HTT) interacting proteins. ... Read more

Product Description
This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to huntington's disease (also Artificial insemination; Chronic Progressive Chorea; Chronic progressive hereditary chorea; Degenerative Chorea; Hereditary Chorea; Hereditary Chronic Progressive Chorea), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on huntington's disease. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms. ... Read more

Customer Reviews (1)

Good For Your Grandma
This book is a VERY remedial introduction to the "world wide web" and is written for someone who thinks a computer is just a typewriter hooked up to a television.And since the internet changes every second, this book was outdated before it even went to print.Don't waste your money on this book - everything inside can be found online for free.

I've purchased nearly every book on Amazon about HD, and I am very sorry to say that the body of knowledge on HD is frighteningly sparse.There really are no good books on HD unless you want to know the history of the disease or read about a particular family's struggle.

For up to date medical information, the best resource, hands down, is The Huntington's Disease Lighthouse at [...]. ... Read more

Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

Product Description
This text is a comprehensive review of research into animal models and humans with HD from neurochemical, neuroanatomical and behavioural perspectives. It focuses on neural transplantation studies in rodent and primate models of HD. Studies demonstrating that foetal brain tissue transplants can reverse the neurodegenerative and behavioural pathology of HD animal models are presented. In addition, the final section discusses recent clinical studies on the advantages, future directions and ethical considerations of cell transplantation for HD. ... Read more