Product Description
Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. ... Read more

Product Description
Case Studies in Immunology, Fifth Edition, cites major topics of immunologyas the background to a selection of real clinical cases that serve to reinforceand extend the basic science. This new edition vividly illustrates the importance of anunderstanding of immunology in diagnosis and therapy. As well as being a valuable review aid, Case Studies in Immunology introduces in a clinical setting the major common disorders of immunity, including hypersensitivity types I-IV and autoimmunedisorders such as lupus and multiple sclerosis. It also describes and explains the consequences of some of the most important immune deficiencies. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the disease or disorder. An end-of-case summary, questions, and discussion points finish each case. Case Studies in Immunology can be used as a stand-alone book, or asa clinical companion alongside Immunobiology, Sixth Edition (ISBN 0-8153-4101-6) and The Immune System, Second Edition (ISBN 0-8153-4093-1).

Key Features:

Contains FIVE new cases bringing the total number of cases included to 47: Hereditary Periodic Fever Syndromes;Interleukin Receptor-associated Kinase Deficiency; Common Variable Immunodeficiency; Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked Disease; Celiac Disease.

Each case describes real events and symptoms from case histories, ensuring that the reader is presented with, assesses, and evaluates a realistic clinical situation.

Full-color illustrations, photographs, and micrographs throughout complement the text.

Contains helpful case summary notes in margin.

Cases end with a discussion and question section; this useful pedagogic tool is designed to highlight lessons learned from individual cases.

Can be used as a clinical companion to Immunobiology, Sixth Edition, and The Immune System, Second Edition. ... Read more

Customer Reviews (11)

just what i asked for
book came quickly and in the condition specified when i ordered it; could not ask for more

Case Studies in Immunology: A Clinical Companion (Geha, Case Studies in Immunology: A Clinical Companion)
It was in excellent condition even with the few underlined sections or highlighted parts, in my opinion those only make text books more valuable.

Great for a second pass at immunology
My use of this book is probably a little different from most of the other reviewers here.My medical school immunology course used a different book (Lippincott's Immunology, which is passable); a year later, while studying for my USMLE step 1, I didn't want to waste time re-reading the basics in a textbook (i.e. I didn't need to read a 20-page chapter about the difference between innate and adaptive immunity).I also wasn't satisfied with the level of detail in my review books, which were fine for physiology but very weak in describing genetic immunodeficiency syndromes.

That's the benefit of this book-- the basics are there, but are integrated into cases alongside more "advanced" concepts.If you already have a good grasp on basic immunology (adaptive vs. innate, B vs. T, CD4 vs. CD8, Th1 vs. Th2), this is a much easier way to learn the complexities of immunodeficiency syndromes or autoimmune diseases (most of the cases in this book are one or the other).As such, I would definitely recommend using this book for a boards review of immunology (if you can spare a day or two from your review schedule to read it-- it's about 300 pages).It covers ALL the relevant immunology-- I can't imagine being surprised by an immuno question on test day if you know what's in here.

That said, I would NOT recommend this book as a starting point for learning immunology (and based on some of the other reviews here, that is unfortunately how it has occasionally been used).This was never meant to be a stand-alone immunology text, and I honestly can't imagine why it would be assigned as the text for an undergraduate introductory course. There are several good introductory immunology books out there-- the one I used is Sompayrac's "How the Immune System Works," but you have lots of choices.Once you have the basics, though, this book is excellent for making the jump to clinical immunology.

Great Companion text for any immunology course
Great Companion text for any immunology course.Shows clinically relevant cases and exemplifies how and why certain themes apply to medicine.

Case Studies in Immunology
This book is a great companion to Janeway's Immunobiology!It allows you to read real life cases that relate to the material you are learning about in Immunology.Great Buy:) ... Read more

Product Description
A straightforward introduction to Immunology which gives a concise, well explained approach for students with the aid of simple and useful diagrams. The second edition has been updated to underline the changes in this fast-moving field. ... Read more

Product Description
Progress in Basic and Clinical Immunology is a result ofthe 14th European Immunology Meeting -- EFIS 2000, held inPoznan, Poland, on 23--27 September 2000. EFIS 2000 gatheredover 1400 immunologists from all over the world. It was anexceptionally memorable meeting for a number of reasons: 1) it washeld in the last year of the century and the millennium, thusprovoking conclusions of past achievements of immunology andprojections for the future; 2) it was held in Poland, a country thatis a symbol of struggle for freedom for a large number of scientistsoriginating from the `Eastern Bloc' countries; and 3) EFIS celebratedits 25th anniversary at this occasion. This comprehensive volumecontains 62 chapters grouped into 11 sections: T-cells, ImmuneReceptors, Antigen Presentation/Dendritic Cells, Cytokines,Immunodeficiencies, Autoimmunity, Allergy/Inflammation, Immunotherapy,Vaccines, Tumor Immunology, and Cancer Immunotherapy. ... Read more

Product Description
Despite the fact that advanced bioinformatics methodologies have not been used as extensively in immunology as in other subdisciplines within biology, research in immunological bioinformatics has already developed models of components of the immune system that can be combined and that may help develop therapies, vaccines, and diagnostic tools for such diseases as AIDS, malaria, and cancer.

In a broader perspective, specialized bioinformatics methods in immunology make possible for the first time a systems-level understanding of the immune system. The traditional approaches to immunology are reductionist, avoiding complexity but providing detailed knowledge of a single event, cell, or molecular entity. Today, a variety of experimental bioinformatics techniques connected to the sequencing of the human genome provides a sound scientific basis for a comprehensive description of the complex immunological processes.

This book offers a description of bioinformatics techniques as they are applied to immunology, including a succinct account of the main biological concepts for students and researchers with backgrounds in mathematics, statistics, and computer science as well as explanations of the new data-driven algorithms in the context of biological data that will be useful for immunologists, biologists, and biochemists working on vaccine design. In each chapter the authors show interesting biological insights gained from the bioinformatics approach. The book concludes by explaining how all the methods presented in the book can be integrated to identify immunogenic regions in microorganisms and host genomes. ... Read more

Customer Reviews (1)

Bioinformatics at work
The huge majority of bioinformatics (BI) books seem to treat the topic as an end in itself. I have to admit, there is a lot to enjoy in the algorithms people have developed and in clever implementations. Often, though, the calculations appear to be fine art, to enjoy in abstract, or for creating point solutions to isolated problems.

This book breaks the mold. It addresses every aspect of immunology, using BI as the tool and as the unifying language for discussing immunology's many aspects. The content gets off to a slow start, starting with two chapters describing the topic and its importance. The next three chapters summarize a few of the basic algorithms: alignment and multiple alignment, motif-finding, Gibbs sampling, clustering, and neural networks. The discussion is competent, and the authors' handling of neural nets stands out from the crowd of BI books. Still, the pace is too brisk and the range of topics is too narrow to recommend this book as a general BI text.

It's not one, and never meant to be. That section just reminds the knowledgable reader of the mathematical tools and BI terms to be used in the remaining nine chapters. Here's where an immunology background will help a lot. I know, because I lack one. Still, the discussion holds to a level that a determined reader with a general bio and BI background can follow. Even at my barely-following level, it's exciting stuff.

At this writing, the 2005 H5N1 bird flu is all over the front pages, so medical response to emerging viruses is on people's minds. This book explores the whole range of issues in immunological response to the threat: identifying specific viral features that stand out as vaccine targets, understanding the immunological mechanisms that need to be engaged, evolution of the pathogens to emerging human resistance, and the ways that human variation affects the decisions in medicine and public policy.

That last surprised me, but makes perfect sense. Different human populations have slightly different sets of alleles for immunological response. It's one of the reasons that humanity does so well in a world of ever-changing antigenic threats. As a species, we have so many possible responses to any challenge that someone somewhere is bound to be able to survive almost any pathogen around. The range of immune-response alleles, their different sensitivities and combinations, and their distributions in different gene pools helps decide how a vaccine must be crafted. If the vaccine antigen generally triggers a good response in African Americans but not East Asians, it answers only part of the question.

This is the first text I know that really shows BI at work in clinically important ways. It's a guided tour of the world of immunological attacks and responses, measured using BI tools - not just pathogens, but allergens, autoimmune triggers, and even possible cancer treatment. Beginners will have a rough time following the discussion, but this is a book for people deep in their specialty. It gave me a good idea of what questions are asked, and why, and how BI answers them. I look forward to seeing an immunological researcher's review of this text - from the pure BI stand point, it's narrow, but shows the versatility of the tools it chooses.

//wiredweird ... Read more

Product Description
Integrating Population Outcomes, Biological Mechanisms andResearch Methods in the Study of Human Milk and Lactation isthe product of the 10th Conference of the International Society forResearch on Human Milk and Lactation, held on September 15--19,2000, in Tucson, Arizona. The presented sessions at the meeting are asdiverse as the volume itself. These sessions include the impact ofmicronutrient deficiencies during lactation on maternal and infanthealth, the premature infant, developmental immunology, breastfeedingin the industrialized world, and viral transmission in milk. Wheneverpossible, the sessions were organized to include human populationresearch, research showing the biological underpinnings of the effectson human health, and important methodological issues. This volume is acontemporary and influential tool for human milk biologists,breastfeeding epidemiologists, biochemists, immunologists, clinicalspecialists,and all professionals and researchers in the field. ... Read more

Product Description

Until recently innate immunity was viewed as the poorer relative of the sophisticated adaptive immune response. We now know, however, that these ‘higher’ immune responses are actually underpinned by an elegantly hewn system of innate immune surveillance. Discovered first by developmental biologists, again by immunologists, and even by sociologists, Toll receptors have revolutionized our understanding of innate immunology. Although a small part of a complex system, Toll receptor biology compels us to revisit existing models of self – non-self recognition.

Product Description
This state-of-the-art reference provides the practitioner with up-to-the-minute data on mycology of clinical significance, focusing on the increased presentation of fungal infections in immunocompromised, AIDS, and geriatric patients. ... Read more

Product Description
Comprised of essays by top scholars in the field, this volume offers detailed overviews of philosophical issues raised by biology.

• Brings together a team of eminent scholars to explore the philosophical issues raised by biology
• Addresses traditional and emerging topics, spanning molecular biology and genetics, evolution, developmental biology, immunology, ecology, mind and behaviour, neuroscience, and experimentation
• Begins with a thorough introduction to the field
• Goes beyond previous treatments that focused only on evolution to give equal attention to other areas, such as molecular and developmental biology
• Represents both an authoritative guide to philosophy of biology, and an accessible reference work for anyone seeking to learn about this rapidly-changing field

Product Description
Immunology: A Short Course, Sixth Edition introduces all the critical topics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers:

• Toll-like receptors, their ligands and intracellular activation pathways
• The key role of activation induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination.
• The autoimmune regulator (AIRE) gene in self-tolerance and autoimmunity
• T and B cell activation and the immunological synapse, as well as characterization and mechanisms of action of T regulatory cells

Praise for the previous edition:

"This book is clearly a precious resource for undergraduate, graduate and medical students alike… For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest."
ANNALS OF BIOMEDICAL ENGINEERING

"… an excellent beginner's guide… the authors have done a terrific job of providing an overview of the field."
YALE JOURNAL OF BIOLOGY AND MEDICINE ... Read more

Customer Reviews (13)

Great for beginners
I am using this book in conjunction with another and this one is much easier to understand.It clearly outlines what the cells functions are and is well written.It was written in a more logical order so you are able to see the big picture before learning all the small details which helps me in learning quite a bit.

great
Fast delivery, good condition... a little more highlighting than I was expecting, but still good. Thanks.

Easy read, great color pictures!
The Coico Immunology book is what I am currently using as my (required) textbook for medical school Immuno course. It is a GREAT text, especially this new edition. Fabulous color pictures (I am all about the pics!) and easy to read text. Plus, it's not a huge volume, so everything is summed up comprehensively but succintly (leaving nothing out, without being a tome). Highly recommended textbook.

gets the job done
Some of the pictures are a little lame but it does a good job of laying things out.

Ordering for second time
I love this book! I'm a 4th year medical student and I have 3 other texts on immunology and this is the one that I keep going back to. I loaned it to a friend and it burned in a fire so here I am ordering it again. The text is simple and to the point. The diagrams are suitable and I found them detailed enough. This is my bedtime reading book. ... Read more

Product Description
In the field of immunology, type 1 diabetes has become one of the major areas of investigation with studies that span from characterization of key molecules to trials for the prevention of the disease.
Type 1 Diabetes : Molecular, Cellular and Clinical Immunology communicates both the background and the most recent understanding of this disorder, which will almost certainly be central to elucidating the etiology of autoimmunity, and in particular of organ specific autoimmunity. The book covers immunogenetics, immunopathogenesis, epidemiology, disease prediction and clinical application of current knowledge.
Both scientists seeking to understand and prevent type 1 diabetes/autoimmunity as well as physicians caring for families with type 1 diabetes will be interested in this book. ... Read more

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Univ. of Pennsylvania, Philadelphia. An integrated and comprehensive account of advances in B and T lymphocyte development. For researchers and clinicians interested in hematopoiesis, immunology, cancer biology, and gene therapy. ... Read more

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Since the subject of arenaviruses was visited by Current Topics in Microbiology and Immunology 14 years ago, enormous advances have been made in this area. The receptor for several arenaviruses, alpha-dystroglycan, was identified, the replication strategy of these viruses was decoded, and application of a reverse genetics system for studying viral gene function and viral biology is well underway. In addition to reviewing these advances, Volume I includes discussion of arenaviral molecular phylogeny, reservoirs in rodents and clinical diseases caused by both new world and old world arenaviruses. ... Read more

Product Description
Therelatively new field of cord blood transplantation is characterized by its rapid progress. Cord Blood: Biology, Immunology, Banking, and Clinical Transplantation encompasses the present state of cord blood cells, banking and transplantation and provides insight to the future of this progressive field. This cutting-edge book, composed of 17 chapters by 34 authors, covers the excitement, history and recent innovations in phenotype, genomics, and function of cord blood hematopoietic stem, progenitor, and immune cells, clinical cord blood transplantation, and public and private banking. It is a valuable resource for physicians, and scientists interested in these and related areas.

The four main focus areas include:

The phenotyping, genomics and function of hematopoietic stem and progenitor cells from cord blood
The immune cells and immunology of cord blood and cord blood transplantation
Cord blood banking from public and private perspectives
Current clinical cord blood transplantation and efforts to enhance the broadness of applicability of this clinical field through scientific and clinical innovation ... Read more

Product Description

This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.

Product Description

• Blends biology, clinical science, genetics, and molecular biology of the immune system to provide a complete account of our knowledge of immunology
• New features include full-color artwork and design, over 50 new figures, and text that has been completely revised to reflect the very latest references
• Incorporates a variety of pedagogical aids to assist students in the learning process, including chapter outlines, objectives, and summaries, as well as a self-evaluation section
  

Customer Reviews (3)

BUYER BEWARE!!
I purchased this book a few months ago for the course I am taking. The book is well written and provides a wealth of information.
HOWEVER, BEWARE!!This book does NOT come with ANY type of internet or computer support of ANY kind!!!There is no CD with the book, no supporting website, etc. So if you have even the simplest of questions that you would rather not bother your professor with (or have at 2 am when you seem to be alone), there is nothing to help you with this.
Like I said, the book is wonderful but the Author and/or publishing company needs to get with the 21st Century as well as with "Today's Student".

Klaus must update or perish
Just a quick note: Dr. Elgert's text is 10 years old.. 10!That's before the human genome came out, and what's more, the book is hopelessly outdated on a number of points.First of all, a lot of good science has been put out in the 10 years since its publication. Second, his illustrations look like their were made in MSPaint (and they very well may have been).Moreover, he reprintedhis old edition at some point, but in black and white, and on rough, heavier paper.Buyer beware - the cover is identical.



LUCKILY.. if you don't go to Virginia Tech, I'm sure you're not in danger of exposure to this opaque anachronism of a textbook...

Clear and Easy to read
It's very good textbook, easy to read and understand. I'm waiting for the new and up-to-date edition from the author, if possible. ... Read more

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Rhode Island Hospital, Providence. Provides a mechanistic view of the key aspects of the inflammatory response seen in critical illness. Emphasizes the cells and mediators involved in the innate inflammatory response and the pathways employed to combat infection or respond to the injury. ... Read more

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In recent decades, immunology has been one of the most exciting -- and successful -- fields of biomedical research.Over the past thirty years, immunologist have acquired a detailed understanding of the immune system's unique recognition mechanism and of the cellular and chemical means used to destroy or neutralize invading organisms.This understanding has been formulated in terms of the clonal selection theory, the dominant explanation of immune behavior.That story is the subject of The Generation of Diversity. ... Read more