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The most concise, comprehensive, and up-to-date medical microbiology & immunology review!Gives students the high-yield information they need to prepare for the USMLE Step 1 and course exams. Completely updated throughout, the new edition covers developments in HIV, hepatitis, smallpox, SARS, and more. Features case discussions, USMLE-style questions, and a USMLE-style practice exam. ... Read more

Customer Reviews (4)

Too confusing
The immunology section of this book is the most convoluted reading I have had in all my readings for the step 1.Frankly, the figures are far superior in explaining what the author is trying to convey.Maybe this book was helpful for others but it just frustrated me and did not expand any more than what was already more concisely described in first aid.Bottom line, not worth the time.

execllent
the immunlogy section is extra ordinary with concise yet comprehensive ! itsimplified not only for usmle but also for medical carrier, so it should study first before the other topics.
I think the book needs more thorough answers for usmle questions as most of us purchase for usmle reviews not for text !

Almost excellent
I love this book but the reason i gave this book 4 stars is just because they didn't bother to correct some mistakes of the seventh edition. In this edition (eighth), on page 41 (Chapter 7) Botton note says: Pseudomonas aeruginosa {endotoxin} has the same mode of action. Refering to Diphtheria toxin. It should be {exotoxin}. Another example (to show you a few) is in the same chapter on page 43 table 7-13, it says:
Nervous system
Gram-positive rods:
Clostridium tetani>>>>inhibit acetylcholine release
Clostridium botulinum>>>>inhibit glycine release
As you can see they are mismatched.
So this book is almost perfect, excellent contents but with a few mistakes in some concepts.

Currently the best Micro Review Book
Yes folks, this is better than Made Rediculously Simple. Well, let me rephrase that. I like this book a lot better. Now dont get me wrong, MRS is a good book and I use both, but if I could only choose one, I would go with this one.

First of all, it just came out this summer. So it does have some recent updates that MRS doesnt have, particularily with the antibiotics. I also think it offers better clinical scenarios and presentations of the various bugs. It is in depth with what you need to know, yet concise at the same time. Ive used it for class, and for board prep. Another thing, is that it doesnt have those silly mnemonics that can often be very far fetched and cumbersome. And yet one more thing, but may sound silly, is that I like the font and layout better. It makes more judicious use of tables as well to drive home key points.

And the best of all, is that it has over 600 USMLE style questions. I thought for the most part, they were indicative of what you will see on the real thing. Last but not least, it also has a great section devoted to medical immunology, so no need to buy another separate book.

So if you have money to get both, do it. But if you are trying to choose between the two, I say get this one. The LANGE Pharm and Board review book is good too. Good luck. ... Read more

Product Description
“... Boxed summaries at the start of each subchapter and examples illustrated throughout the book highlight the key points and provide clarity. Most chapters conclude with a short problem set, summarising the basic concepts and prompting further thought. This clear text is a useful starting point for anyone aspiring to solve a biological question using systems biology approaches.” –Phenotype, 2010

Systems biology is a highly topical discipline at the intersection of biochemistry, cell biology, computer science, and systems engineering.

This course book in systems biology is tailored to the needs of advanced students of biology, engineering, and computer science. It has a companion website with solutions to questions in the book, additional chapters, and computer implementations of systems biology models.

The book is a follow-up of the very successful Systems Biology in Practice and incorporates the feedback and suggestions of many lecturers worldwide.

The interdisciplinary team of acclaimed authors have worked closely together to ensure a comprehensive coverage of the topic in a fluent and compelling style.

Further material is available on www.wiley-vch.de/home/systemsbiology

Systems Biology in Practice - Praise from the reviews:

"...this is one book that I bought for myself as soon as it was published." –British Journal of Occupational Therapy

"This resource does an admirable job of bringing the readers to a level where they can pursue more advanced study and research." –IEEE Engineering in Medicine and Biology Magazine

"… I am confident that biologists everywhere will benefit from having a copy to hand." –Theoretical Biology and Medical Modelling ... Read more

Product Description
Founded in 1959, by John Kendrew, the Journal of Molecular Biology was the first journal devoted to this new and revolutionary science. To celebrate the thirtieth anniversary of the Journal, the current editor, Sydney Brenner, has selected a number of papers from the first hundred volumes. They include the seminal papers on genetic regulation by Jacob and Monod and on allostery by Monod, Changeux and Jacob. Also included are many important papers on structural biology and molecular genetics and papers reflecting the initial developments in DNA cloning and sequencing.
Of value to all biologists with an interest in the molecular basis of living systems, the book is a personal selection by the Editor. Readers are encouraged to compare it with their own choice from the Journal of Molecular Biology. ... Read more

Product Description
Reproductive Immunology is a compilation of researcharticles presented during the VII International Congress ofReproductive Immunology which was held in New Delhi, India on 27-30October 1998. The articles pertain to the following six major themes:

i. Molecular and Immunological Aspects ofSperm--Egg Interactionii. Embryonic--EndometrialCross-Talkiii. Immunobiology of Pregnancyiv. Autoantibodies andInfertilityv. Immunocontraceptionvi. Mucosal Immunology andReproductive Tract Infections. The first section deals with our current understanding of varioussteps involved in fertilization. The functional significance of spermsurface mannosidase and glutathione S-transferases to bind zonapellucida is described. The role of zona pellucida glycoproteins inthe binding of sperm, induction of acrosome reactions and avoidance ofpolyspermy is discussed. In the second section, the role of variouscytokines, growth factors and immunomodulatory agents in implantationof embryos is described. In the field of reproductive immunology, oneof the major issues is to explore the successful gestation of thehistoincompatible fetus in the uterus of an immunologically competentmother. The Proceedings presents the issues of paternal antigens atthe feto-maternal interface and shows that Th2-type of immunity isinvolved in normal successful conception. The role of membrane-boundand soluble HLA-G in protecting the fetus from the lytic activities ofmaternal uterine and peripheral blood natural killer (NK) cells isalso presented. Nature's experiments suggest that antibodies against sperm-specificantigens are responsible for infertility in some women. Thepossibility that an immunogenetic background contributes to productionof sperm-immobilizing antibodies in infertile women is discussed inthe section on autoantibodies and infertility. The Proceedingspresents the issue of Th1-type cytokines in inducing recurrentspontaneous abortions of unexplained etiology. The roles ofB2-glycoprotein 1 (B2-GP1)-dependent anticardiolipinantibody, lupus anticoagulant, antiphospholipids, anti-thyroidantibody and anti-nuclear antibody in miscarriages are also described.

The rising global human population, particularly in the developingcountries, has driven the need for new and safer methods ofcontraception. Fertility regulation by vaccines is thus an interestingproposition. The section on contraceptive vaccines discusses thelatest advances in this area and describes the current status ofvaccines based on BhCG, sperm antigens, zona pellucidaglycoproteins, and riboflavin carrier proteins. The issues of mucosal immunity and strategies for enhancing localgenital immune responses to combat HIV infection is discussed. Therole of inflammatory and related cytokines in chorioamnionitis isdescribed.The contents of this Proceedings describes various facets ofreproductive immunology which will help us to design strategies tocombat genital infections and miscarriages caused by immunologicaletiology. Descriptions of the molecular basis of gamete recognition,implantation and survival of the allogenic fetus will help indesigning strategies for overcoming infertility and also newcontraceptive approaches. The Proceedings will be useful toresearchers and clinicians involved in basic or applied research inthe disciplines of reproductive biology, reproductive immunology, andobstetrics and gynecology. ... Read more

Product Description
Image analysis and flow cytometry are complementary techniques which provide new insights into essential aspects of cell biology. This book presents an up-to-date overview of current ideas and methods in these domains. It consists of three parts. Part I, "Membrane Dynamics and Function", deals with adhesion molecules, membrane pump dynamics, membrane fusion and endocytosis, membrane potential, T-cell homing and cytoskeleton, etc. The second part focuses on problems of cell proliferation, chromosome analysis and sorting, apoptosis, imaging cytometry of fixed and living cells, image analysis for gene mapping from flow-sorted chromosomes, chromatin organization, and liposome-mediated delivery of DNA binding drugs. The third part covers data management systems, cell sorting techniques and microscopy. ... Read more

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The Scripps Research Institute, La Jolla, California. Advanced immunological research in six areas such as immune response against tumors, interleukin-5, and fas and fas ligand. 15 contributors, 2 U.S. Halftone illustrations and color plates. ... Read more

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This outstanding resource offers comprehensive presentations of the latest basic knowledge and the most advanced research on neuropeptides of the respiratory tract–covering the structure, receptors, molecular biology, and function of each important neuropeptide and examining how they relate to disease.Demonstrates the utility of immunohistochemistry, autoradiography, molecular biology, smooth muscle contraction, and glandular secretion for the study of neural function both in vitro and in vivo!Separating the airways into upper and lower areas to allow comparisons between the nasal and pulmonary systems, Neuropeptides in Respiratory Medicine.provides detailed chapters on vasoactive intestinal peptide, neuropeptide Y, sensory neuropeptides, and nitric oxidediscusses peptide antagonists and metabolic pathways, offering insight into the regulation of neuropeptide actionsdescribes the interaction of neuropeptides with cancer, rhinitis, asthma, chronic bronchitis, cystic fibrosis, and immunityoutlines the hypothesis that damage to neutral endopeptidase facilitates respiratory inflammationdelineates controversies in the roles of sensory nerve neurogenic inflammation and sensory nerve neurotransmittersexplains the postulated roles of known neurotransmittersand much more! ... Read more

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This single-source reference presents current knowledge of the mechanisms of airway injury and repair in response to environmental factors such as chemicals, infectious agents, pollution, mechanical irritants, and toxic agents. ... Read more

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This book is about the structure, functional activities and regulation of the expression and adhesive properties of the leukocyte integrins. The description of their functional activities is done within the context of general leukocyte effector functions during immune and inflammatory responses. The book also summarizes our current knowledge on the leukocyte integrins signal transduction ability, their identified ligands, and the clinical consequences of their absent expression in the Leukocyte Adhesion Deficiency syndrome. Finally, the book addresses the potential therapeutic effectiveness that leukocyte integrin-specific reagents might have in a variety of inflammatory and immunological diseases. ... Read more

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It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embryonic development, innate and adaptive immune regulation and maintenance of cellular homeostasis. Agents that manipulate the signaling of these receptors are being used or showing promise towards the treatment and prevention of many human diseases such as rheumatoid arthritis, coronary heart disease, transplantation rejection, insulin resistance, multiple organ failure and cancer.

Product Description
The book summarises the current understanding of the Nervous -, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. In addition to the fundamental physiological and pathophysiological mechanisms, which are presented in detail, some clinically relevant subjects are also presented, such as inflammation, asthma and allergy, autoimmune disease, immunodeficiency and the acute phase response.

• A comprehensive presentation of neuroimmune biology

• Introduces the subject matter to the uninformed reader

• Contains basic information, theoretical considerations and up-to-date clinical chapters

• The clinical chapters will be helpful to practising physicians

... Read more

Product Description
It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements. ... Read more

Product Description
Instant Notes titles focus on core information and aredesigned to help undergraduate students come to grips with a subjectquickly and easily.

This new edition has been amended throughout, new sections have beenadded on aging and gender and the immune system, and diagrams havebeen redrawn for improved consistency of style.

Instant Notes in Immunology, Second Edition provides concise yetcomprehensive coverage of immunology at an undergraduate level,providing easy access to the core information in the field. The bookcovers all important areas in immunology in a format which is idealfor learning and rapid revision. Also features MCQs and answers whichtest knowledge and understanding. ... Read more

Customer Reviews (2)

Nice Experience
Hi it was nice experience overall.
I wanted this book since long time. New edition was expensive and did not think that it would too different from the old one. So instead of going for new one i went for old one. Its condition is new.
Thanks for being prompt in sending.
thanks
Umesh

A real gem
People often make the mistake of hitting the bigger books with the hope that they will gain a more complete understanding of a subject. However the problem with such an approach (particularly when beginning a subject) is that more often than not, one loses sight of the key concepts and broad principles. This where i feel this book is a gem. The strength of this book is that each chapter succinctly provides you with all the main points you need to know about each subtopic. In this way you are given a solid basis and contextual understanding, enabling you to gain a deeper appreciation of immunology from larger texts.
At the start of each immunol topic in your course, read the corresponding chapter in this book first, then use your lecture notes or larger texts to fill the gaps/details.

This happens to be one of a very few review books i've kept in my extensive library.

Dr A.M.

... Read more

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Cleveland Clinic Cancer Center, OH. Summarizes ten years of scientific and therapeutic innovation and offers clinicians and clinical researchers practical knowledge about the nature, diagnosis, and treatment of this disease. Discusses the role of surgery, molecular aspects, and systemic therapy. DNLM: Carcinoma, Renal Cell. ... Read more

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For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field. ... Read more

Customer Reviews (1)

Excellent general resource
This book is a new but excellent resource for high school students.I will be able to use it in both my regular and advanced biology classes. The book tackles some very tough topics and it is the first I have seen that allows experts to translate difficult topics into something useable and valuable to high school students. The topics are also very timely for students interested in how biology relates to the news.I wish the book and the Anatomy and Physiology companion volumes were available in Spanish. ... Read more

Product Description
System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers. ... Read more

Product Description
This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment.For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic.Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature.The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment.Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of the popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field. ... Read more

Customer Reviews (1)

A great primer for researchers
I'm a mathematics Ph.D. student who's working in computational oncology, meaning that I study cancer from a mathematical/engineering point of view (conservation of mass, oxygen and glucose transport, etc.) and create computer models for study. This biophysical viewpoint has been fruitful, but I've found that to make further progress, an understanding of the cellular biology is required. Furthermore, a lack of vocabulary makes it difficult to communicate with the clinical/medical community.

That's where this book comes in: it gives a great, expansive overview of cancer that is difficult to come by in the mathematical world. In places, it is perhaps too detail-oriented (which specific proteins do what and how, e.g., in DNA repair), but that's the nature of the beast, and I feel that it's very important for mathematical biologists to be exposed to this. The text gives a good sampling ranging from epidemiology, genetics and epigenetics (gene expression), oncogenes, tumor suppresor genes, DNA repair, cell cycle, and most approaches to therapy.

Because this edition was published in late 2005, it's quite up-to-date, and in that regard, the papers cited are very useful to the student and researcher for further exploration and paper writing. Probably one of the greater weaknesses is in the figures in the earlier genetics sections: the diagrams are not particularly helpful in actually illustrating the complex processes. Overall, though, this has been very helpful for me in bridging the gap between mathematical biology and oncology. I'd highly recommend this text for anybody who desires to learn more about the biology of the cancer, regardless of where they're coming from. ... Read more