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Sickle Cell Anemia: more books (100)

My Life with Sickle Cell Anemia by Tysheba Randall, 2004

Pain and Sickle Cell Anemia.(discussion of patient-controlled analgesia): An article from: The Hastings Center Report by David Resnik, Marsha Rehm, et all 2001-05-01

SICKLE CELL ANEMIA: An entry from UXL's <i>UXL Complete Health Resource</i>

Hydroxyurea extends life span in adult sickle cell anemia. (Upto 9 years of Follow-up).: An article from: Internal Medicine News by Heidi Splete, 2003-05-15

Estimating rates of psychosocial problems in urban and poor children with sickle cell anemia. (Special Issue on Women and Children): An article from: Health and Social Work by Oscar A. Barbarin, Charles F. Whitten, et all 1994-05-01

In vitro antidrepanocytary actvity (anti-sickle cell anemia) of some congolese plants.(Drug overview): An article from: Phytomedicine: International Journal of Phytotherapy & Phytopharmacology by P.T. Mpiana, D.S.T. Tshibangu, et all 2007-02-01

MODULATION OF FETAL HEMOGLOBIN IN SICKLE CELL ANEMIA. by Alex. Saleh, 1998-01-01

Crystals in My Bones: One Sickle Cell Anemia Journey by Bernice Brewer, 2006-01-04

Reduce stroke risk in sickle cell anemia patients.(Clinical Rounds): An article from: Pediatric News by Bruce Wilson, 2007-03-01

Some Blood and Heart related Diseases: Including some known risk factors for the diseases.Modifying the controllable risk factors.Deep Vein Thrombosis (DVT) and Sickle cell anemia. by Gabriel Fashoro, 2008-06-23

Sickle-Cell Anemia Disease Medical Guide by Qontro Medical Guides, 2008-07-09

Sickle cell anemia: An entry from Thomson Gale's <i>Gale Encyclopedia of Alternative Medicine</i> by Beth Kapes, 2001

Sickle Cell Anemia by David Gerrick, 1978-06

Concentrations of B vitamins and homocysteine in children with sickle cell anemia.(Original Article): An article from: Southern Medical Journal by Jodi B. Segal, Edgar R., III Miller, et all 2004-02-01

lists with details

Newborn Screening Brochurs And Educational Materials - New York State Department
Sickle cell disease (sickle cell anemia or homozygous S disease)a disorder ofthe hemoglobin (oxygencarrying part) of red blood cellsnot to be confused
http://www.wadsworth.org/newborn/disorders.htm

Extractions: Disorders Identified by the New York State Newborn Screening Program Biotinidase deficiency (bio-TIN-i-dase)lack of an enzyme (biotinidase) prevents the body from properly absorbing or recycling the vitamin biotin. Severe skin rashes, vision and hearing impairment, and brain damage can be prevented by special biotin supplements given daily. Occurs in about 1 of every 80,000 newborns. Branched-chain ketonuria (branched-chain KEE-tone-u-ree-ah)also called maple syrup urine disease (MSUD) because the urine has a maple syrup-like odor resulting from the body's inability to break down some components of food protein. Again, this is due to the lack of an enzyme. Treatment with a special diet can prevent life-threatening complications. Occurs in about 1 of every 268,000 newborns. Galactosemia (ga-LAK-toe-see-me-a)a milk sugar (galactose) cannot be broken down by the body due to the lack of an enzyme. A diet low in galactose can prevent life-threatening complications. Occurs in about 1 of every 57,000 newborns. HIV (Human Immunodeficiency Virus) HIV is the virus that causes AIDS. The test checks for the presence of HIV antibodies. If a baby is HIV positive, this means that the mother is infected with HIV in all cases, and that the baby has been exposed to the virus. Only a quarter of babies who were exposed to HIV actually have infection. HIV positive newborns should have special medical care and need repeat testing to see if they are infected. Their mothers also need special medical care.
Rutgers Focus - March 31, 2003 - Jackson Lears Looks At Luck
and Disease Identity in TwentiethCentury America (Johns Hopkins University Press,1997) and Dying in the City of the Blues sickle cell anemia and the
http://ur.rutgers.edu/focus/

Extractions: Moralists, churchmen and political leaders (at least in public pronouncements) have railed for centuries against gambling as a corrosion of the social order and a corruption of personal character. Yet, in America and worldwide, the populace continues to raise one beseeching hand to the heavens while tossing the dice with the other.
WebMD - Gene Testing (Sponsored)
Singlegene diseases such as sickle cell anemia lie at one end of this spectrum.If you have two defective genes, you have sickle cell anemia.
http://my.webmd.com/content/article/3/3204_201

Extractions: Sponsored by DNA Sciences cg_addbib('burgess','9614824','http://www.cma.ca/cmaj/vol-158/issue-10/1309.htm','','Burgess MM, Laberge CM, Knoppers BM. Bioethics for clinicians: ethics and genetics in medicine. CMAJ 1998;158:1309-13.'); cg_addbib('caulfield','10569090','http://www.cma.ca/cmaj/vol-161/issue-9/1122.htm','','Caulfield T. Gene testing in the biotech century: are physicians ready? CMAJ 1999;161:1122-4'); cg_addbib('marteau','9522800','http://www.bmj.com/cgi/content/full/316/7132/693','','Marteau TM, Croyle RT. Psychological responses to genetic testing. BMJ 1998;316:693-696.'); Gene Testing The stage is set for a revolution in medicine growing out of our understanding of genetics. This revolution will affect not only diseases we think of as genetic, but most other diseases as well. While the ability to repair defective genes still lies years, or even decades, in the future, some genetic testing is here today cg_cite("caulfield") Contents of this page...
DUMCL: Ovid Tutorial
If you are also interested in other types of sickle cell anemia, you can explodethe broad term Anemia, Sickle Cell to pick up the more specific types, namely
http://www.mclibrary.duke.edu/respub/guides/ovidtut/explode.html

Extractions: Ovid Tutorial Duke University Medical Center Library Explode is a function that allows you to expand your search strategy to include additional, more specific terms. If you are also interested in other types of Sickle Cell Anemia, you can explode the broad term Anemia, Sickle Cell to pick up the more specific types, namely Hemoglobin SC Disease and Sickle Cell Trait which are indented under it in the Tree Display. When you explode a term the system will automatically retrieve all citations indexed to that term as well as all the citations indexed to the terms indented under it. Tree for Anemia, Sickle Cell Select Subject Heading Explode Focus Scope Note Anemia, Sickle Cell (9256) Hemoglobin SC Disease (362) Sickle Cell Trait (1214) Sample retrieval with and without Explode ("exp") : Search History Results Display Anemia, Sickle Cell/ Display exp Anemia, Sickle Cell/ Display Note: Exploding Anemia, Sickle Cell retrieves 9836 citations. This includes citations indexed to the more specific terms Hemoglobin SC Disease and Sickle Cell Trait , as well as Anemia, Sickle Cell
Ovid: Search Form
Thomas MD. Falletta JM. Influence of penicillin prophylaxis on antimicrobial resistancein nasopharyngeal S. pneumoniae among children with sickle cell anemia.
http://www.mclibrary.duke.edu/respub/guides/ovidtut/print2.html

Extractions: Citation Manager Help Logoff Click in the boxes to select the first 2 citations. Then scroll down the list of references to the Citation Manager Berkovitch M. Papadouris D. Shaw D. Onuaha N. Dias C. Olivieri NF. Trying to improve compliance with prophyla ctic penicillin therapy in children with sickle cell disease. [Clinical Trial. Journal Article. Randomized Controlled Trial] British Journal of Clinical Pharmacology. 45(6):605-7, 1998 Jun. (THE DUKE MED CTR LIBRARY HAS THIS TITLE; CHECK FOR HOLDINGS) UI Woods GM. Jorgensen JH. Waclawiw MA. Reid C. Wang W. Pegelow CH. Rogers ZR. Iyer RV. Holbrook CT. Kinney TR. Vichinsky E. DeBaun MR. Grossman NJ. Thomas MD. Falletta JM. Influence of penicillin prophyla xis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophyla ctic Penicillin Study II. [Clinical Trial. Journal Article. Multicenter Study. Randomized Controlled Trial] Journal of Pediatric Hematology/Oncology. 19(4):327-33, 1997 Jul-Aug.
HON - News : Hunting Down A Cure For Sickle Cell Disease
SUNDAY, Sept. 22 (HealthScoutNews) While a cure remains elusive,victims of sickle cell anemia are living longer, healthier lives.
http://www.hon.ch/News/HSN/508766.html

Extractions: HealthScoutNews Reporter SUNDAY, Sept. 22 (HealthScoutNews) While a cure remains elusive, victims of sickle cell anemia are living longer, healthier lives. The most common inherited blood disease in the United States, sickle cell anemia affects about 80,000 Americans, primarily blacks. Another 2 million Americans have the defective gene that causes the disorder, making them potential carriers. Thanks to improvements in diagnosis, treatment and research, half of those with the condition are now more than 50 years old. Until recently, people with sickle cell rarely survived childhood, according to the National Human Genome Research Institute. "I have five adult patients, one more than 60 years old, who watch out for themselves. They are good, cooperative patients who make sure they optimize their care," says Dr. Kenneth Algazy, a clinical associate professor of medicine at the University of Pennsylvania School of Medicine. Sickle cell anemia is caused by the production of faulty hemoglobin, a key component of red blood cells. Hemoglobin carries oxygen from the heart to all parts of the body.
Medic-Planet Sickle Cell Anemia
sickle cell anemia See also Anemias, Blood, Dehydration, Genetic diseases, Jaundice,Malaria, Osteomyelitis, Pneumonia, Stroke, Back to the Index page
http://www.medic-planet.com/MP_article/internal_reference/Sickle_cell_anemia
Quest Diagnostics - Women's Health - Prenatal Genetic Testing - Sickle Cell
sickle cell anemia affects over 72000 people in the United States. Sicklecell anemia affects over 72,000 people in the United States.
http://www.questdiagnostics.com/patient/womenshealth/sickle_cell.html

Extractions: Cervical Cancer Screening Sexually Transmitted Disease Testing Chlamydia Human Papillomavirus Herpes HIV ... Gonorrhea Prenatal Genetic Testing Cystic Fibrosis Sickle Cell Chromosome Analysis Prenatal Screening Maternal Serum Screening Breast Cancer Testing Ovarian Cancer Testing Osteoporosis Testing ... Osteoporosis Testing Sickle Cell Sickle cell anemia affects over 72,000 people in the United States. It is caused when two copies of an altered hemoglobin gene are inherited, one from the mother and one from the father. This altered version of the gene causes some of the molecules that carry oxygen to tissues throughout the body to occasionally cluster together, affecting the shape and flexibility of the red blood cells. There is no cure for sickle cell anemia, but treatment can greatly reduce the pain and improve quality of life. Is testing for sickle cell anemia for me? Is testing for sickle cell anemia appropriate for me? top of page Sickle cell anemia is caused by a change in the hemoglobin gene that originated many thousands of years ago. It is an advantage in areas such as Africa, the Mediterranean basin, the Middle East, and India, where malaria causes a great number of deaths. People that carry the sickle cell trait in one of the hemoglobin genes resist malaria better. For that reason, sickle cell anemia is more common among people whose ancestors came from sub-Saharan Africa, South America, Cuba, Central America, Saudi Arabia, India, Turkey, Greece and Italy. Sickle cell anemia affects approximately one in every 655 African-Americans and approximately one in every 1,000 Hispanic-Americans. Approximately one in twelve African-Americans is a carrier of the disease.
HealingWell.com - Medifocus Guides - Sickle Cell Anemia
HealingWell Medcenter Medifocus Guide sickle cell anemia (HM012) Introduction Whatare the most common symptoms of sickle cell anemia?
http://www.healingwell.com/medcenter/sickle_cell_anemia.asp

Extractions: Sickle cell disease (CSD) is an inherited blood disorder, characterized primarily by chronic anemia and periodic episodes of pain. The underlying problem involves hemoglobin, a component of the red cells in the blood. The hemoglobin molecules in each red blood cell carry oxygen from the lungs to the body organs and tissues and bring back carbon dioxide to the lungs. By occluding blood vessels sickle cells cause vascular injury. This vaso-occlusion, which is responsible for most of the severe complications of sickle cell disease, can occur wherever blood flows. This process produces the periodic episodes of pain and ultimately can damage the tissues and vital organs and lead to other serious medical problems.
Mystery Of The Crooked Cell - Extension
the Crooked Cell , an inquirybased activity developed by Boston University Schoolof Medicine's CityLab to explore the molecular basis of sickle cell anemia.
http://www.unc.edu/cell/files/extensions/mystery/mystery.html

Extractions: This website is an internet extension of "Mystery of the Crooked Cell", an inquiry-based activity developed by Boston University School of Medicine's CityLab to explore the molecular basis of sickle cell anemia. For more information on CityLab or "Mystery of the Crooked Cell", we invite you to explore the CityLab website Introduction Glossary Protein Structure and Synthesis Diploid Genetics/Genetics of Inheritance ... Multimedia I ntroduction - To be considered successful, a scientific experiment should not only provide answers to scientific questions, but should lead to further questions and stimulate the curiosity of the scientist performing the experiments. The constant quest for more knowledge on a particular subject is the essence of scientific research. "Mystery of the Crooked Cell" is a laboratory exercise examining the molecular basis of the genetic disease Sickle Cell Anemia. If it is successful, you are now more familiar with how and why people develop this disease. And, hopefully, you are left with a new-found curiosity about related subjects such as genetics, protein structure, malaria and gene therapy. The purpose of this extension is to provide you with basic information necessary to start you on your quest for more information on several topics related to "Mystery of the Crooked Cell". This should not be considered a definitive collection of websites on any particular subject, but rather a starting point. Allow your curiosity to be the driving force, and enjoy your journey!
The Health Library Blood And Lymphatic Systems
sickle cell anemia. What is Sickle Cell Disease? Sickle Cell Disease Associationof America. sickle cell anemiaNemours Foundation for Kids.
http://healthlibrary.stanford.edu/resources/internet/bodysystems/blood3.html

Extractions: Acute Lymphoblastic Leukemia (ALL) Acute Myeloid Leukemia (AML) Anatomy Anemia ... Spleen Disorders Blood and Lymphatic Systems: Page 1 Page 2 Anemia General Anemia:MEDLINEplus Anemia:Mayo Clinic Anemia in the Elderly:American Academy of Family Physicians Ambulatory Management of Common Forms of Anemia :American Academy of Family Physicians ... Understanding Anemia:netLibrary Aplastic Anemia Aplastic Anemia:Aetna InteliHealth Aplastic Anemia:Johns Hopkins Cancer Center Fanconi Anemia Fanconi Anemia:Mt. Sinai School of Medicine Fanconi Anemia Research Fund Fanconi Anemia:GeneReviews Hemolytic Anemia Hemolytic Anemia:Aetna InteliHealth Autoimmune Hemolytic Anemia:American Autoimmune Related Diseases Association Cold Agglutinin Disease:American Autoimmune Related Diseases Association Iron-Deficiency Anemia Iron-Deficiency Anemia:University of Maryland Medicine Iron-Deficiency Anemia:Iron Disorders Institute Iron Deficiency in Adults:Australian Iron Status Advisory Panel Iron Deficiency in Children:Australian Iron Status Advisory Panel Megaloblastic (Pernicious) Anemia Megaloblastic (Pernicious) Anemia:University of Maryland Medicine Pernicious Anemia:American Autoimmune Related Diseases Association See also Sickle Cell Anemia Sickle Cell Anemia:MEDLINEplus What is Sickle Cell Disease?: Sickle Cell Disease Association of America
DAVID GOLDE Interview
For example, one very important disease that theoretically can be cured by insertionof a gene is sickle cell anemia, because in that condition there is an
http://www.accessexcellence.org/AB/CC/golde.html

Extractions: The following is an excerpt from an interview with David Golde that took place at the "Winding Your Way through DNA" symposium at the University of California San Francisco in 1992. David W. Golde, MD heads the Division of Hematologic Oncology at Memorial Sloan-Kettering Cancer Center, New York City. Excerpted from the symposium transcripts with permission of the University of California, San Francisco. Q. How are genetic research and biotechnology affecting our understanding of blood itself and blood-related disorders? DG. Well, the biotechnology revolution and recombinant DNA have perhaps had their major affect on diseases of the blood and the cells that circulate in blood. We've developed a number of recombinant products. These are proteins that are produced either in bacteria or yeast. These proteins for the first time allow us to control the number and function of blood cells so that we can increase the red blood cell count and treat anemia. We can increase the white blood cell count in order to allow people to fight off infections. And that is a new thing, that is an exciting thing. It is the first time in medical history that we've been able to positively affect what we call host defense. That is, the ability of the body to fight off disease. Q.
News And Events At The NIH Clinical Center
02); Unraveling the Pain of sickle cell anemia (11/25/02); ClinicalResearch Information System Contract Announced (9/17/02); Type
http://www.cc.nih.gov/ccc/aboutcc/media_resources/media.html

Extractions: Reporters and editors seeking information about the Clinical Center or its ongoing research can call 301-496-2563 for assistance. The Clinical Center Office of Communications can provide background information and arrange interviews with our experts. Clinical Center News and Events Patient Recruitment Updates Clinical Center News Releases, Backgrounders and Notices: Serial MRI Tracks Brain Changes in West Nile Virus Encephalitis Unraveling the Pain of Sickle Cell Anemia Clinical Research Information System Contract Announced Type O blood donors needed ... CC Search For more information about the Clinical Center,
Sickle Cell Study
have initiated a pilot project that has taken them out of their Bethesda labs andinto the local community to study a new treatment for sickle cell anemia.
http://www.cc.nih.gov/ccc/aboutcc/media_resources/news_features/sickle.html

Extractions: Jan. 5, 1999 Scientists from the Warren Grant Magnuson Clinical Center at the National Institutes of Health have initiated a pilot project that has taken them out of their Bethesda labs and into the local community to study a new treatment for sickle cell anemia. "This pilot provides a unique opportunity because there is clearly a need for more and better treatment options for people living with this debilitating disease," says Dr. Frederick Ognibene, senior investigator in the Clinical Center's Critical Care Medicine Department. "We have been lucky enough to find people in our community who want to see an end to this disease and have been caring enough to participate in our pilot project." "This research initiative and outreach efforts demonstrate the Clinical Center's commitment to identifying and meeting the health needs of our community," said Dr. John I. Gallin, director of the Clinical Center. "Clinical research is essential to the discovery of new knowledge that leads to better health for everyone." Researchers from the Clinical Center and the NIH have visited local churches, hospitals, and support groups to talk with community members about the promising treatment and elicit participation in the study. The group is working with Howard University and Children's National Medical Center, as well as organizations such as the Armstead-Barnhill Foundation. The Foundation serves the community by developing new medical research options for sickle cell anemia patients.
Hematopoietic Chimerism After BMT For Sickle Cell Anemia
Hematopoietic Chimerism After BMT for sickle cell anemia. Stable Mixed HematopoieticChimerism After Bone Marrow Transplantation for sickle cell anemia.
http://www.bloodline.net/stories/storyReader$3177

Extractions: Login Stable Mixed Hematopoietic Chimerism After Bone Marrow Transplantation for Sickle Cell Anemia M.C. Walters, M. Patience, W. Leisenring, Z.R. Rogers, V.M. Aquino, G.R. Buchanan, I.A.G. Roberts, A.M. Yeager, L. Hsu, T. Adamkiewicz, J. Kurtzberg, E. Vichinsky, B. Storer, R. Storb, K.M. Sullivan Biology of Blood and Marrow Transplantation 7:665-673 (2001) ABSTRACT: Download a PDF version of the full article Carden Jennings Publishing Co., Ltd. Related Content 1998 European Group for Blood and Marrow Transplantation A "Constant" Problem ABMT in Patients with Low-Grade or Mantle Cell Lymphoma Allogeneic Marrow Grafts for Aplastic Anemia ... Minimum TBI in Aplastic Anemia with Unrelated Donor BMT
Hematopathology Index
PelgerHuet anomaly (bilobed neutrophils) on smear, microscopic; Sicklecell anemia on smear, microscopic; sickle cell anemia on smear
http://medlib.med.utah.edu/WebPath/HEMEHTML/HEMEIDX.html

Extractions: The following images are present: Normal bone marrow, medium power microscopic Normal bone marrow, high power microscopic Normal bone marrow smear, high power microscopic Normal bone marrow smear, high power microscopic ... Rouleaux formation with red blood cells on smear, microscopic Hypochromic microcytic anemia on smear, microscopic Hypochromic microcytic anemia on smear, microscopic CBC with iron deficiency anemia, diagram Hypersegmented neutrophil with megaloblastic anemia on smear, microscopic ... Aplastic anemia, bone marrow, low power microscopic Acute lymphocytic leukemia in marrow, medium power microscopic Acute lymphocytic leukemia on smear, microscopic Chronic lymphocytic leukemia on smear, microscopic Acute myeloblastic leukemia on smear, microscopic ... Chronic myelogenous leukemia, Philadelphia chromosome, karyotype Benign reactive lymph node, low power microscopic [IPX]
American Red Cross: Donation Information
These special red blood cells are used to treat sickle cell anemia patients whomust receive frequent blood transfusions. What is sickle cell disease?
http://chapters.redcross.org/midatlanticblood/info/minority.html

Extractions: A community blood supply should reflect the communities it serves, and our communities are rich in cultural and ethnic diversity. Unfortunately, the current blood donor base in the United States does not fully reflect our diverse populations. For example, of the 5% of healthy Americans that choose to donate blood nationally, only 1% are African-Americans. For several reasons. First, some rare blood types are found only in minority communities. In addition to the common ABO blood types, extremely rare antigens such as Duffy- and U- are found exclusively in the African-American population. Secondly, higher frequencies of types O and B blood are found in the African-American community, and it is these blood types that the Red Cross runs low on most frequently. The Mid-Atlantic Region also has a large demand for red blood cells that are phenotypically matched for Rh, K, S and Fya or Fyb antigens. These special red blood cells are used to treat sickle cell anemia patients who must receive frequent blood transfusions.
HealingWell.com Library - News And Articles
HealingWell.com Community, Information, Resources, Search Site Search Web HealthPortal Diseases and Conditions Genetic Congenital sickle cell anemia
http://healingwellhemonco.subportal.com/health/Diseases_and_Conditions/Genetic_C
The Mailman Center For Child Development
Respiratory Problems in Children SchoolBased Asthma Intervention program MaternalAssessment in Management of Pain in sickle cell anemia Disease Severity
http://pediatrics.med.miami.edu/Research.htm

Extractions: RESEARCH Mailman Center faculty, staff and trainees conducted a number of research studies related to prevention, early identification, intervention and evaluation. Examples include: long range tracking of school performance of children with disabilities; examination of the relationship between variables such as maternal age, neonatal conditions, and later life experiences; comparisons of effectiveness and efficiency of methods for testing otoacoustical emissions; cultural differences and coping; genetic linkage studies of familial neuromotor development and studies of the needs of individuals with balance dysfunction; new techniques for vision screening for young children with disabilities, and parent/child interactions. Scientific presentations at conferences, workshops and seminars are part of the dissemination efforts. Research activities
SICKLE CELL DISEASE
People with sickle cell disease either have sickle cell trait or sicklecell anemia. WHAT HAPPENS WHEN YOU HAVE sickle cell anemia?
http://www.mckinley.uiuc.edu/health-info/dis-cond/misc/sicklecd.html

Extractions: Sickle Cell Disease is a hereditary blood disorder that affects the oxygen-carrying component of blood, the red blood cell. In other words, it is manifested by diseased red blood cells that have a sickle shape. Red blood cells have proteins called hemoglobin. Hemoglobin transports oxygen from your lungs to every part of your body. When a normal red blood cell (with normal hemoglobin) releases its oxygen, it maintains its discoid shape. However, when a diseased red blood cell containing sickle hemoglobin releases its oxygen, the appearance of the cell can change from discoid to sickle-shaped. This is to say that the sickle cell shape is caused by the sickle hemoglobin within a particular red blood cell. Possible health problems may include fatigue, breathlessness, rapid heartbeat, delayed growth, susceptibility to infections, skin ulcers, and vision problems. NORMAL HEMOGLOBIN vs. SICKLE HEMOGLOBIN While sickle hemoglobin and normal hemoglobin carry the same amount of oxygen, two major differences exist between the two kinds of cells. First, they differ in the way they flow through the blood vessels. Normal hemoglobin is found in disc-shaped red blood cells that are soft (like a bag of jelly), which enables them to easily flow through small blood vessels. Diseased red blood cells, which are sickle-shaped and are hard (like pieces of wood), often get stuck in small blood vessels and stop the flow of blood. The second difference between the two types of cells is their longevity. Sickle cells do not live as long as normal cells. Normal, healthy cells can survive for about 120 days, while the more fragile sickle cells can survive for about 60 days or less. Unfortunately, the body cannot make new red blood cells as fast as it loses sickle blood cells. As a result, a sickle cell patient has fewer red blood cells and less hemoglobin than normal red blood cells. This decreased hemoglobin (called anemia), in turn, results in less oxygen being available for use by the cells of the body.

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