41. Florida State University College Of Medicine Digital Library ankylosing spondylitis Clinical Resources. Miscellaneous ankylosingspondylitis Clinical Resources Arthritis Foundation Homepage; http://fsumed-dl.slis.ua.edu/clinical/rheumatology/autoimmune/spondyloarthropath

Clinical Resources by Topic: Rheumatology Ankylosing Spondylitis Clinical Resources Pediatrics Radiology Pathology Clinical Guidelines ... Miscellaneous Resources See also: Musculoskeletal Clinical Procedure Resources General Rheumatology Clinical Resources Ankylosing Spondylitis Patient/Family Resources Harrison's Principles of Internal Medicine 15th Ed.-2001: Table of contents Medical Library subscription INFO Chapter 320: Approach to Articular and Musculoskeletal Disorders Table of contents Introduction Access document Articular versus Nonarticular Site of Origin: Access document Inflammatory versus Noninflammatory Disorders: Access document Clinical History: Access document Physical Examination: Access document Laboratory Investigations: Access document Diagnostic Imaging in Joint Diseases: Access document Rheumatologic Evaluation of the Elderly: Access document Approach to the Patient: Access document Chapter 315: Ankylosing Spondylitis, Reactive Arthritis, and Undifferentiated Spondyloarthropathy Table of contents Introduction Access document Ankylosing Spondylitis Access document Epidemiology Access document Pathology Access document Pathogenesis Access document Clinical Manifestations Access document Laboratory Findings Access document Radiographic Findings Access document Diagnosis Access document Treatment: Access document Chapter 16: Back and Neck Pain Table of contents Introduction: Access document Anatomy of the Spine: Access document Approach to the Patient: Access document Causes of Back Pain: Access document Congenital Anomalies of the Lumbar Spine:

42. AS Dietary Primer AS ankylosing spondylitis. Please refer to the glossary at the end of this paperfor more information. Modality and Expression of AS and autoimmune Conditions. http://www.kickas.org/as_dietary_primer.shtml

HLA B-27 KickAS.org Search Main page Kickas.org Forums Forums Main Index General Discussion Main AS Support Group Helpful Tips Social Security Sporting ASKickers Treatments, Drugs and Alternatives Starch-Free Diet: NSD Issues AS Pharmacy Alternatives For Laughter and Contemplation Jokes Inspirational Stories and Quotes Creative Kickers' Corner Literary Discussions Site Information Technical Support Private Forums (must register) - Friends and Family Support - Men Only - Women Only Medical Center Contract Substance Prescriptions AS Patient Guidebook Pain Map Concept of Disease Modification Diet Center London AS Diet Molecular Mimicry AS Dietary Primer Technical Papers ... AS Food Guide Support Center AS Kickers World Map KickAS Photo Gallery AS Kickers Stories KickAS Banners ... Frequently Asked Questions The AS Dietary Primer John Merchant aureq@inreach.com Background: Much of the recent useful research into AS has been conducted at Kings College, London, by Doctor Alan Ebringer and his colleagues, together with his work at Middlesex Hospital, London. Their findings have been summarized in this primer for use by asweb.com, created and supported by Tony Browneller, as an outgrowth in support of the asweb, created and supported by Brian Harris.

43. Molecular Mimicry And Ankylosing Spondylitis: Possible Role Of A Novel Sequence been suggested that the mechanism for the apparent autoimmune condition in AS 25 rheumatoidarthritis (RA) patients and 97 ankylosing spondylitis (AS) patients http://www.kickas.org/medical/as10molemim/as10molemim-03.html

4. Discussion Antibody elevations to Klebsiella pneumonias in AS patients were first reported in 1983 [5] and those original observations have since been confirmed in various centres [6]. Furthermore, antibodies to other gram negative organisms such as Escheric-hia coli, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella spp, Shigella spp, and Yersinia enterolitica have not been found to be elevated in AS patients [5]. Additionally, a strong association between HLA-B27 and AS has been known for over 20 years [1]. These two observations were linked in 1987 [7] in the form of an amino acid homology between B*2705 and K. pneu-moniae nitrogenase. The data presented in this paper suggests a new sequence homology between B*2705 and another protein present in K. pneumoniae, the pulD secretion protein of the starch debranching pullulanase enzyme system (Table 1). Whilst the pulD sequence does not display the 100% homology shown with K. pneumoniae nitrogenase a similarity is nonetheless present in the form of a tetramer, (residues 596-599) (DRDE) and B*2705 (DRED). The pulD sequence (residues 596-599) only differs from the DRED sequence in B*2705 (74-77) and K. pneumoniae

44. Autoimmune Inner Ear Disease (AIED) Both allergy and traditional autoimmune disease such as ankylosing spondylitis,Systemic Lupus Erythematosis (SLE), Sjoegren's syndrome (dry eye syndrome http://www.tchain.com/otoneurology/disorders/autoimmune/aied.html

Autoimmune Inner Ear Disease (AIED) Timothy C. Hain, MD Last edited: 1/2003. Please read our AIED defined How common is it Diagnosis Treatment Education Index Autoimmune inner ear disease or "AIED" consists of a syndrome of progressive hearing loss and/or dizziness which is caused by antibodies or immune cells which are attacking the inner ear. The classic picture is reduction of hearing accompanied by tinnitus (ringing, hissing, roaring) which occurs over a few months. Variants are bilateral attacks of hearing loss and tinnitus which resemble Meniere's disease , and attacks of dizziness accompanied by abnormal blood tests for self-antibodies. About 50% of patients with AIED have balance symptoms. The immune system is complex and there are several ways that it can damage the inner ear. Both allergy and traditional "autoimmune disease" such as Ankylosing spondylitis , Systemic Lupus Erythematosis (SLE), Sjoegren's syndrome (dry eye syndrome), Cogan's disease , ulcerative colitis, Wegener's granulomatosis, rheumatoid arthritis, and scleroderma can cause or be associated with AIED. Another multisystem disease

45. University Of Glasgow - Immunology - Max Field Our research involves investigating genetic predispositions to autoimmune diseaseas demonstrated in ankylosing spondylitis, as well as septic arthritis which http://www.gla.ac.uk/departments/immunology/people/field.htm

NEWS SUBJECTS PEOPLE EDUCATION ... POSITIONS AVAILABLE Max Field, BSc MD FRCP Senior Lecturer in Rheumatology Septic arthritis; Medical education; Genetics of autoimmune disease; Cytokines in synovitis. m.field@clinmed.gla.ac.uk Tel: +44 (0) 141 211 4688 Fax: +44 (0) 141 211 0414 Centre for Rheumatic Diseases, Level 3, QEB, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, MAIN AREA OF RESEARCH Our research involves investigating genetic predispositions to autoimmune disease as demonstrated in ankylosing spondylitis, as well as septic arthritis which may predispose to tissue disorders. BIOGRAPHY Dr Field graduated from University in London in 1977, undertook a clinical career initially in Oxford and subsequently joined the Charing Cross and Westminster University Medical School in London working as a lecturer in the Kennedy Institute of Rheumatology. Dr Field joined the Centre for Rheumatic Diseases in 1991. PROJECTS Septic Arthritis This clinically based project has assessed septic arthritis because this is one of the most rapidly destructive arthritic diseases known to man. We have been investigating mechanisms of this joint destruction and predisposition to infection.

46. Arthritis Information Page...Rheumatoid, Osteoarthritis, Juvenile, Gout, (AS) An (AS) ankylosing spondylitis usually affects They are thought to be autoimmune,which means your immune system attacks the connective tissue in your joints. http://www.cyberbreezes.com/health/arthritis.htm

Save $$$ on Health Supplements! But man has a sinful nature, and only God can help him to overcome it. Arthritis Twenty two million Americans are afflicted with the chronic joint pain of arthritis. Arthritis is characterized by an inflammation and/or pain in the joints. Common arthritic joints include the knees, wrists, elbows, fingers, toes, hips, shoulders, neck and back, but it can also strike in any of the body's 200 joints. At present, the word "arthritis" refers to more than 190 rheumatic diseases in which one or more joints become inflamed. Typical symptoms include pain, swelling, stiffness, and deformity of one or more joints. It can happen suddenly or gradually. Some people may feel a sharp burning or grinding pain, while others compare the pain to a toothache. Moving the affected joint usually hurts, although sometimes there is only stiffness. (3) "Joint disorders are the number one medical problem in the world," says Dr. Luke Bucci, a researcher and clinical nutritionist. Besides arthritis, there are other diseases which include aches and pains in connective tissues such as ligaments, tendons, muscles and bursae. If not treated, the prolonged inflammation can eventually cause severe damage to the joint itself. (3) The joints in the human body are cushioned by cartilage. In people with arthritis, the cartilage membranes become inflamed, puffy and warm. In days gone by, physicians could only offer pain medication and cortisone as a quick fix, but now there is new hope through nutrition. Through nutrition it is now possible to rebuild the cartilage in our joints using nutrients like glucosamine with chondroitin. (3)

47. Arthritis, Pain Management, Cancer Pain, Back Pain, Shingles, Compression Fractu in the joints; and rheumatoid arthritis, an autoimmune disease that and organs, suchas fibromyalgia, lupus, ankylosing spondylitis, osteoporosis, scleroderma http://gulfcoastpain.com/arthritis.htm

v Gulf Coast Pain Management Benign Pain ARTHRITIS Even if you don't have arthritis, you probably know somebody who does. Nearly 43 million Americans one in six people, or 15% of the population have some kind of arthritis. Arthritis is a general term used to describe more than 100 chronic diseases of the joints, bones, and muscles. The two most common and best known types of arthritis are osteoarthritis, a wearing away of the cushioning cartilage in the joints; and rheumatoid arthritis, an autoimmune disease that causes painful and often disabling joint inflammation. Arthritis also includes a range of diseases that affect the muscles, connective tissues and organs, such as fibromyalgia, lupus, ankylosing spondylitis, osteoporosis, scleroderma, gout, and even Lyme disease. Symptoms can range from pain and stiffness in a few joints to serious and severe damage to many joints and internal organs. The symptoms and seriousness of arthritic diseases vary widely. It can be a mild condition you can control with over-the-counter pain relievers or it can cause severe pain and inflammation that can drastically change your life. Left untreated, some forms of arthritis can be life-threatening. You may also have heard arthritis called rheumatism: the terms are used interchangeably by some people today, and arthritis specialists are still called rheumatologists.

48. CCHS Clinical Digital Library American autoimmune Related Diseases Association Homepage Medical InformationList of documents ankylosing spondylitis Access document. HealthSouth Disease http://cchs-dl.slis.ua.edu/patientinfo/rheumatology/autoimmune/spondyloarthropat

Patient/Family Resources by Topic: Rheumatology Ankylosing Spondylitis Patient/Family Resources Pediatrics Spanish Miscellaneous See also: General Rheumatology Patient/Family Resources Ankylosing Spondylitis Clinical Resources MD Consult: Homepage Health Sciences Library subscription INFO Patient Handouts Table of content Low and Sciatica Back Pain (Comprehensive Version): Access document Arthritis Foundation: Homepage Disease Center: List of documents Ankylosing Spondylitis Access document American College of Rheumatology: Homepage Patient Information: List of documents Ankylosing Spondylitis: Access document American Academy of Family Physicians (familydoctor.org): Homepage Self Care Flowcharts: List of documents Lower Back Pain: Access document University of Birmingham (U.K.) Dept of Rheumatology: Homepage Patient Information: List of documents Arthritis Help: A Primer on Rheumatic Diseases: Table of contents A Few Definitions Access document General Features of Inflammatory Arthritis Access document Treatments Access document American Pain Foundation: Homepage Consumer Health Information: List of documents Arthritis: Modern Treatments: Access document Arthritis in its Many Forms: Access document Arthritis Pain: Access document Arthritis and Exercise: Access document American Autoimmune Related Diseases Association: Homepage Medical Information: List of documents Ankylosing Spondylitis Access document MEDLINE plus Medical Encyclopedia: Table of contents Ankylosing Spondylitis: English Spanish Arthritis: English Spanish Joint Pain: English Spanish InteliHealth

49. CCHS Clinical Digital Library ankylosing spondylitis Clinical Resources. Miscellaneous ankylosingspondylitis Clinical Resources Arthritis Foundation Homepage; http://cchs-dl.slis.ua.edu/clinical/rheumatology/autoimmune/spondyloarthropathie

Clinical Resources by Topic: Rheumatology Ankylosing Spondylitis Clinical Resources Pediatrics Radiology Pathology Clinical Guidelines ... Miscellaneous Resources See also: Musculoskeletal Clinical Procedure Resources General Rheumatology Clinical Resources Ankylosing Spondylitis Patient/Family Resources Harrison's Principles of Internal Medicine 15th Ed.-2001: Table of contents Health Sciences Library subscription INFO Chapter 320: Approach to Articular and Musculoskeletal Disorders Table of contents Introduction Access document Articular versus Nonarticular Site of Origin: Access document Inflammatory versus Noninflammatory Disorders: Access document Clinical History: Access document Physical Examination: Access document Laboratory Investigations: Access document Diagnostic Imaging in Joint Diseases: Access document Rheumatologic Evaluation of the Elderly: Access document Approach to the Patient: Access document Chapter 315: Ankylosing Spondylitis, Reactive Arthritis, and Undifferentiated Spondyloarthropathy Table of contents Introduction Access document Ankylosing Spondylitis Access document Epidemiology Access document Pathology Access document Pathogenesis Access document Clinical Manifestations Access document Laboratory Findings Access document Radiographic Findings Access document Diagnosis Access document Treatment: Access document Chapter 16: Back and Neck Pain Table of contents Introduction: Access document Anatomy of the Spine: Access document Approach to the Patient: Access document Causes of Back Pain: Access document Congenital Anomalies of the Lumbar Spine:

50. Links For Juvenile Arthritis ankylosing spondylitis A good site on ankylosing spondylitis with a listing ofsupport groups and other good The Scleroderma autoimmune Support Ring. http://www.geocities.com/wncjra/links.html

The following is a list of web sites that deal with juvenile arthritis. This list will be growing as I find more links. If you know of any others that would be good to add to this page, please e-mail us. Select a category below or look through them all: Information Support Juvenile Rheumatoid Arthritis Juvenile Lupus ... Web Rings Information The Arthritis Foundation The American Juvenile Arthritis Organization The Washington Bone and Joint Clinic This site has a great article on Juvenile Arthritis. Webmed Website This is a medical site full of information about all kinds of illnesses. It requires you to sign-in perform accessing the information. It is a free site. The American College of Rheumatology Use the index on this site to find a pediatric rheumatologist in your area. Return to the top Support The Arthritis Net for Kids A wonderful site for children of all ages who have arthritis. Parents will love it too! Kids Get Arthritis Too Another great site for both children and parents Under 21 A page for people under 21 who have chronic illnesses. Reaching Out to Children with Juvenile Arthritis Information on helping children with Juvenile Arthritis.

51. Klebsiella Pneumoniae* ankylosing spondylitis (autoimmune disease). The autoimmune disease, ankylosingspondylitis, is thought to be a possible sequela of Klebsiella infection. http://www.medinfo.ufl.edu/year2/mmid/bms5300/bugs/klebpne.html

MMID Home Page Bugs Index Cases Index Klebsiella pneumoniae* Diseases Sites and Sources Diagnostic Factors Virulence Factors ... Commentary Synonyms none Classification facultative anaerobic, gram- bacteria, rods Diseases Pneumonia fever chills chest pain cough dyspnea tachypnea tachycardia rales lung consolidation cyanosis mucoid sputum current jelly sputum hemoptysis Septicemia fever chills anorexia fatigue lethargy nausea vomiting tachycardia bacteremia Wound infection pus suppuration inflammation erythema pain Burn infection pus suppuration inflammation erythema pain Urinary tract infection (cystitis) pain on urination dysuria frequent urination urgent urination suprapubic pain Ankylosing spondylitis (autoimmune disease) fever anorexia weight loss night sweats fatigue back pain joint pain spinal fusion Sites and Sources GI tract, normal flora oropharynx, normal flora respiratory tract, normal flora lungs, pathogen alcoholics, pathogen burns, pathogen Diagnostic Factors culture on McConkey's agar or EMB pink colonies on McConkey agar gas produced in TSI growth on McConkey's and EMB agars growth on selective media hydrogen sulfide- indole- lactose+ urease+ (weak) no gas-TSI non motile encapsulated Virulence Factors capsule endotoxin adhesin aerobactin antibiotic resistance Treatment and Prevention amikacin cephalosporin gentamicin Commentary Updated: May 11, 1999

52. Children's the meaning of ankylosing spondylitis, symptoms, diagnosis Contact the ankylosingSpondylitits Association, PO Box 5872 Title Understanding autoimmune diseases. http://www.seattlechildrens.org/parents/childcite/SearchResults.asp?KeySubject=1

53. Advanced Search TABLE 1 Ocular Manifestations of autoimmune Disease. Disease, Ocular manifestations. Sjögren'ssyndrome, Keratoconjunctivitis sicca. ankylosing spondylitis, Uveitis. http://www.aafp.org/afp/20020915/991.html

Advanced Search Ocular Manifestations of Autoimmune Disease SAYJAL J. PATEL, LT, MC, USNR and DIANE C. LUNDY, CAPT, MC, USN Naval Medical Center, San Diego, California A PDF version of this document is available. Download PDF now (8 pages / 279 KB). More information on using PDF files. P atients with autoimmune diseases are frequently encountered by family physicians. It is important to understand not only the systemic effects of these diseases but also their ocular manifestations (Table 1) . Most ocular complications involve the cornea but may also include the conjunctiva, uvea, sclera, retina, and surrounding structures (Figure 1) . The majority of these diseases will ultimately need to be referred to an ophthalmologist. See page 937 for definitions of strength-of-evidence levels contained in this article. Rheumatoid Arthritis Approximately 25 percent of patients with rheumatoid arthritis (RA) will have ocular manifestations. These may include keratoconjunctivitis sicca, scleritis, episcleritis, keratitis, peripheral corneal ulceration, and less common entities such as choroiditis, retinal vasculitis, episcleral nodules, retinal detachments, and macular edema. Keratoconjunctivitis sicca, or dry eye syndrome, is the most common ocular manifestation of RA and has a reported prevalence of 15 to 25 percent.

54. Sign Up For Email On Many Allergic And Autoimmune Diseases Rheumatological Immunological Conditions (Allergic and autoimmune Conditions).Allergies Amyloidosis ankylosing spondylitis Antiphospholipid Syndrome Asthma http://www.medicalmailbox.com/rheumimmune.htm

Get periodic email updates with the latest news on hundreds of medical and health related topics all for free! Click here for your free membership to our online weight loss program! Find out about: - Medications and treatment regimens - New and exciting medical websites for specific conditions - Support groups and message boards - Special product promotions - Alternative therapies and much more! Simply check off the boxes adjacent to any of the topics that interest you and fill out the form below. (Allergic and Autoimmune Conditions) Allergies Amyloidosis Ankylosing Spondylitis Antiphospholipid Syndrome Asthma CREST Syndrome Dermatomyositis Eczema Goodpasture Disease Gout Graves Disease Hashimotos Thyroiditis Juvenile Rheumatoid Arthritis Liver Transplant Lupus Lyme Disease Myasthenia Gravis Osteoarthritis Pemphigus Polyarteritis Nodosa Polymyalgia Rheumatica Polymyositis Pseudogout Psoriasis Renal Transplant Rheumatic Fever Rheumatic Heart Disease Rheumatoid Arthritis Sarcoidosis Scleroderma Temporal Arteritis Wegeners Granulomatosis Popular Medical and Health Related Topics Acne Alcohol Cessation Allergies Alternative Medicine Alzheimer's Disease Angina Anxiety Disorders Arthritis Asthma Atherosclerosis Back Pain Breast Cancer Cancer Children's Health Colon Cancer Corrective Vision Surgery Crohn's Disease

55. EMedicine - Ankylosing Spondylitis And Undifferentiated Spondyloarthropathy : Ar A variant, ankylosing tarsitis, is described in children active disease, sacroiliitisand spondylitis are either are the only known autoimmune diseases linked http://www.emedicine.com/med/topic2700.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Rheumatology Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy Last Updated: August 17, 2001 Rate this Article Email to a Colleague Synonyms and related keywords: Marie-Strümpell disease, von Bechterew disease, von Bechterew's disease AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Lawrence H Brent, MD , Chair, Program Director, Associate Professor, Department of Medicine, Division of Rheumatology, Albert Einstein Medical Center, Thomas Jefferson University Lawrence H Brent, MD, is a member of the following medical societies: American Association for the Advancement of Science American Association of Immunologists American College of Physicians , and American College of Rheumatology Editor(s): Kristine M Lohr, MD , Associate Chief, Program Director, Professor, Department of Internal Medicine, Division of Rheumatology, University of Tennessee School of Medicine;

56. Autoimmune Diseases autoimmune diabetes, Hashimoto's thyroiditis . ? ? ? rhematoid arthritis, ankylosing spondylitis http://bric.postech.ac.kr/webzine/content/review/immun/sung4.html

Autoimmune diseases Tel.: (02) 3410-3436 2. Autoimmune diseaseÀÇ Classification°ú Ư¡ 2.1. Autoimmune diabetes(type 1 diabetes) 2.2. Autoimmune diseaseÀÇ ÀÓ»óÀû Ư¡ 2.3. Graves' disease ... 2.13. Sjogren's syndrome Autoimmune disease´Â ÀÓÆı¸ ½½ºÅÛÀÇ ÀÚ±â-ºñÀÚ±â(self-nonself) ±¸ºÐ¿¡ ¹®Á¦°¡ ¹ß»ýÇÏ¿© »ý±â´Â º´ÀÌ´Ù. ÀÌ º´Àº ÁÖ·Î ¿©¼º¿¡°Ô¼­ ¸¹ÀÌ ÀϾ´Âµ¥, ȯÀÚÀÇ ¾à 75%°¡ ¿©¼ºÀÌ´Ù. Åë°èÀûÀÎ °ªÀ» º¸¸é ¹Ì±¹ÀÎ ¾à 20%´Â ¾Ë·ÁÁø 80¿© °³ÀÇ autoimmune disease °¡¿îµ¥ Çϳª¸¦ °¡Áö°í ÀÖ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. Ö±Ù¿¡´Â ¸¹Àº º´µéÀÌ autoimmuneÀÇ °á°ú·Î¼­ ¹ß»ýÇÏ´Â °ÍÀ¸·Î °£Áֵǰí ÀÖ´Ù. ½ÉÁö¾î µ¿¸Æ°æÈ­(atherolsclerosis)ÀÇ °æ¿ì¿¡µµ oxidized LDL¿¡ ´ëÇÑ autoimmuneÀÇ °á°ú·Î ¹ß»ýÇÏ´Â °ÍÀ¸·Î »ý°¢µÇ°í ÀÖÀ¸¸ç, ¸î¸î ¸é¿ªÇÐÀÚµéÀº ´Þ¸® ¿øÀÎÀÌ ¹àÇôÁöÁö ¾ÊÀº ¸ðµç º´Àº autoimmuneÀ» ¿øÀÎÀ¸·Î °£ÁÖÇØ¾ß ÇÑ´Ù°í ÁÖÀåÇÏ°í ÀÖ´Ù. Àμ¿¡´Â ³Ê¹«³ª ¸¹Àº ÀÓÆı¸ ¼¼Æ÷µéÀÌ ÀÖÀ¸¹Ç·Î, ÀÌµé °¡¿îµ¥ ÀϺδ ´Ù¸¥ ±â°ü³·³ ±â´É¿¡ ¹®Á¦°¡ »ý±â°Ô µÈ´Ù. Áï, 60¼¼ ÀÌ»óÀÇ ¿©¼º 50% ÀÌ»óÀÌ ·ù¸ÓƼÁò ÀÎÀÚ¸¦ °¡Áö°í ÀÖ´Ù. µû¶ó¼­ autoimmunity´Â ¸Å¿ì ÈçÇÑ Çö»óÀ̶ó°í ÇÒ ¼ö ÀÖÀ¸³ª, autoimmune disease´Â ±×·¸°Ô ÈçÇÑ Áúº´ÀÌ ¾Æ´Ï´Ù. Autoimmune diseaseÀÇ Classification°ú Ư¡ Autoimmune disease´Â Å©°Ô Àü½Å¼º(systemic autoimmune disease), ±â°ü¼º(organ-specific autoimmune disease)°ú ±× ¹ÛÀÇ °æ¿ì·Î ³ª´­ ¼ö ÀÖ´Ù(Ç¥ 1). Systemic autoimmune diseaseÀÇ °æ¿ì´Â SLE, polymyositis-dermatomyositis, systemic sclerosis°¡ ÀÖÀ¸¸ç ±â°ü(organ)¿¡¼­ ¹ß»ýÇÏ´Â °æ¿ì·Î´Â autoimmune diabetes, Hashimoto's thyroiditisµîÀÌ ÀÖ´Ù. ¾ÕÀÇ µÎ °æ¿ì¿¡ ¸ðµÎ ¼ÓÇÏÁö ¾Ê´Â °ÍÀ¸·Î´Â rhematoid arthritis, ankylosing spondylitis°¡ ÀÖ´Ù.

57. Merck Newsroom ankylosing spondylitis is a chronic, autoimmune disease that primarily affects thespine, usually leading to pain, stiffness and immobility of the lower back. http://www.merck.com/newsroom/press_releases/102802.html

ARCOXIA TM Demonstrated Superior Results Versus Placebo in the Treatment of Ankylosing Spondylitis, a Highly Painful, Inflammatory Disease, in the Primary Efficacy Analysis of a New Study ARCOXIA Also Showed Superior Treatment Effects Over the Non-Steroidal Anti-inflammatory Drug (NSAID) Naproxen NEW ORLEANS, Oct. 28, 2002 In the primary efficacy analysis of a new study, ARCOXIA TM (etoricoxib) demonstrated superior results versus placebo in treating patients with ankylosing spondylitis. The study showed the combined group of patients taking ARCOXIA 90 mg or 120 mg once daily demonstrated significant improvements on the primary measurements of pain, function and global assessments at six weeks versus placebo. A significant difference in efficacy between the patients taking ARCOXIA and patients taking naproxen 500 mg twice daily also was seen at six weeks. Researchers presented the results of the new study at the 66 th "In this study, patients treated with ARCOXIA experienced significant improvements in several types of measurements, including pain, inflammation, global assessments, function and mobility compared to those treated with placebo or naproxen," said Agustin Melian, director of clinical research, Merck & Co., Inc. "This is the first time a COX-2 inhibitor showed statistically significant improvements over a non-selective NSAID in treating this highly inflammatory disease."

58. Abstract: Lack Of Association Of Ankylosing Spondylitis With The Most Common NOD (J Rheumatol 2003;301024). Key Indexing Terms ankylosing SPONDYLITISCROHN'S DISEASE GENETIC PREDISPOSITION TO DISEASE autoimmune DISEASES. http://www.jrheum.com/abstracts/abstracts03/102.html

Search the Journal Home Current Issue Archives Guidelines for Authors ... Contact Info Lack of Association of Ankylosing Spondylitis with the Most Common Susceptibility Alleles to Crohn's Disease ABSTRACT. To investigate whether the 3 most common mutations in the gene that confer susceptibility to Crohn's disease (CD) are also associated with ankylosing spondylitis (AS). DNA from 112 patients with AS and 168 controls of homogenous Spanish ancestry were studied. The frequencies of the pathogenic alleles of , and ) were determined by analysis of the melting curves after hybridization with FRET probes on a Light Cycler real-time polymerase chain reaction (PCR) system. allelic frequencies in controls ( , 0.042) did not significantly differ from patients with AS ( The 3 most common CD mutations do not contribute to disease susceptibility to AS, and therefore do not explain the susceptibility locus for AS in chromosome 16q. (J Rheumatol 2003;30:102-4) CROHN'S DISEASE GENETIC PREDISPOSITION TO DISEASE AUTOIMMUNE DISEASES From the Research Laboratory 2 and Rheumatology Unit, Hospital Clinico Universitario de Santiago, and the Molecular Medicine Unit-INGO, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.

59. Autoimmune Diseases A Patient's Guide to Carpal Tunnel Syndrome. American autoimmune Related DiseasesAssociation. Information ankylosing spondylitis. Learning About Scleroderma. http://www.awhn.org.au/autoimmune.htm

Australian Women's Health Network AWHN Home Page State / Territory Pages Contact Details Women's Health Information Links Search Engines Women's Health Issues Health Program Areas Newsletters ... Relevent Media Resources on Autoimmune Diseases A Patient's Guide to Carpal Tunnel Syndrome American Autoimmune Related Diseases Association American College of Rheumatology Arthritis FAQ ... Back to Home Page

60. Drug InfoNet Doctors' Answers To Frequently Asked Questions - ankylosing spondylitis is inherited, but for some reason not all in a family willhave this problem. It is not clear whether this is a type of autoimmune http://www.druginfonet.com/faq/new/DISEASE_FAQ/Ankylosing_Spondylitis.htm

Doctors' Answers to "Frequently Asked Questions" - Ankylosing Spondylitis These comments are made for the purpose of discussion and should NOT be used as recommendations for or against therapies or other treatments. An individual patient is always advised to consult their own physician. Ankylosing Spondylitis Question: Is Ankylosing Spondylitis hereditary? Answer: The tendency to acquire ankylosing spondylitis is inherited, but for some reason not all in a family will have this problem. It is not clear whether this is a type of autoimmune connective tissue disease or related to other problems with the inherited genes. AS is commonly seen with the histocompatibility antigen HLA-B27. Over 90% of patients will have this antigen (inherited). However, if you inherit the antigen only about 2% of these individuals will develop the disease. Twins run about 50-65%, so there is something besides inheritance which causes the disease. Back to Drug InfoNet Home Page. Back to Doctor FAQ main page.

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