81. Tamlynn's Story A mom shares her story about her daughter's battle with juvenile scleroderma. http://www.expage.com/TammlynnsStory

82. United Scleroderma Foundation Inc. united scleroderma foundation inc. New Mexico Chapter. Long animated contact Unitedscleroderma Foundation The New Mexico State Chapter 4720 Cutting Ave. http://swcybermall.com/scleroderma/

united scleroderma foundation inc. New Mexico Chapter About Our Foundation Upcoming Events About Scleroderma Symptoms ... How You Can Help MISSION STATEMENT It's hard enough to face the debilitating physical and emotional effects of scleroderma, but facing them alone can be devastating. The mission of the United Scleroderma Foundation is to provide educational and emotional support for scleroderma patients and their families. USF is committed to increasing awareness of this devastating disease and raising essential research dollars to determine its cause enhance treatment and find a cure. For More Information contact: United Scleroderma Foundation The New Mexico State Chapter 4720 Cutting Ave. NW Albuquerque, NM E-mail: SuarezTD@aol.com This web site is sponserd by ARTistic Internet Services, Albuquerque, NM

83. Dana's Story A story written by a mom regarding her 18 year old daughter's diffuse scleroderma. http://expage.com/DanasStory

Dana's Story The Wind Beneath My Wings "Go With All Your Heart" Dana was diagnosed with Systemic Scleroderma in September of 1993 when she was ten years old. She also has Raynaud's disease and living in New York City, she struggles with the cold. She has been able to obtain a disability-parking pass from the state and her college. Dana has had bouts with Alopecia Areata, and looses patches of scalp hair, eyelashes, and eyebrows from time to time. As her mother, I find this very hard to handle but she just combs her hair in another direction and goes on. The prognosis for this disease is very troubling but as we have learned, each person has a different set of symptoms. Dana has the support of a fine doctor, Dr. Thomas J.A. Lehman, at the Hospital for Special Surgery in New York City. She continues to take a scary combination of medicine. Dana is fine young woman now and we cannot predict what the future holds for her, or for any of us for that matter, but we know that she lives her life with all her heart. She is my hero, the wind beneath my wings. She makes her father and I proud as well as hopeful that soon we can find a way to stop this awful disease. Until then she knows the world what it means to "go with all your heart". For More Information on Juvenile Scleroderma: Juvenile Scleroderma Network, Inc

84. Index The scleroderma Society of Ontario is committed to promoting increased public awareness,advancing patient wellness and supporting research in scleroderma. http://www.sarnia.com/groups/sso/

Our Mission Statement: The Scleroderma Society of Ontario is committed to promoting increased public awareness, advancing patient wellness and supporting research in scleroderma. About us...... Address Donations Support Groups ... E-Mail Updated on August 29, 2002 Web Master Helen Stys Scleroderma Society of Canada Annual General Meeting Saturday, September 21, 2002 Rustik Restaurant Conference Center Chateauguay Quebec Come Join Us 2002 WALK, ROLL OR RUN Fundraiser Date: Saturday, October 5, 2002 Time: Starting at Noon Location: Springbank Park London Ontario Pledge Form Web space kindly provided by:

85. MedWebPlus Subject Scleroderma A free service to help you find health sciences information quickly and easily.scleroderma A, , GO, Sherry Messick - Personal Story (scleroderma). http://www.medwebplus.com/subject/Scleroderma

Main About MWP Contribute to MWP Contact Us A service of Flexis, Inc. Welcome to MedWebPlus 2.3! A free service to help you find health sciences information quickly and easily. Scleroderma Broader Terms: All Diseases Focussed Subsets: Arthritis Dermatology Immunology Lupus Erythematosus, Systemic ... Rheumatology Web Sites: A GO Road Back Foundation. Using Antibiotics for the Treatment of Rheumatic Disease (Acrobat .pdf file) A GO Scleroderma Federation A GO Scleroderma from A to Z A GO Sherry Messick - Personal Story (Scleroderma) Flexis, Inc. Privacy statement Powered by y-Base

86. Disease Category Listing (136): Scleroderma Clinical Trials scleroderma. Georgia. Marietta scleroderma? New York. NewYork; Rockefeller University Hospital scleroderma Study. International. http://www.centerwatch.com/patient/studies/cat136.html

Clinical Trials: Scleroderma Georgia Marietta; Radiant Research - Atlanta West Are you or a loved one interested in participating in a clinical trial for Scleroderma? New York New York; Rockefeller University Hospital Scleroderma Study International Vienna, Austria; Allgemeines Krankenhaus Wien The ASTIS Trial is an international clinical study for patients suffering from severe, progressive systemic sclerosis (‘scleroderma’). Bobigny, France; Hôpital Avicennes The ASTIS Trial is an international clinical study for patients suffering from severe, progressive systemic sclerosis (‘scleroderma’). Clermont-Ferrand, France; Centre Hospitalier Universitaire de Clermont Ferrand The ASTIS Trial is an international clinical study for patients suffering from severe, progressive systemic sclerosis (‘scleroderma’). Lille, France; Hopital Claude Huriez The ASTIS Trial is an international clinical study for patients suffering from severe, progressive systemic sclerosis (‘scleroderma’). Marseille, France; Hôpital Sainte Marguerite The ASTIS Trial is an international clinical study for patients suffering from severe, progressive systemic sclerosis (‘scleroderma’). Paris, France; Hôpital Saint-Louis

87. Scleroderma - About Scleroderma Next . scleroderma. Edited by Frederick A. Matsen, III, MD Last updatedFebruary 13, 2002 About scleroderma. What is it? scleroderma http://www.orthop.washington.edu/arthritis/types/scleroderma

Home About Us Clinics Physicians ... Contact Us Table of contents About scleroderma What is it? Prognosis Incidence and risk factors ... View article with questions Related articles Raynaud's Phenomenon External links Scleroderma Foundation [Top] Scleroderma Edited by Frederick A. Matsen, III, M.D. Last updated February 13, 2002 About scleroderma What is it? Scleroderma is a disease that can affect the skin, joints , blood vessels, and internal organs. The word scleroderma means "hard skin." Most people with scleroderma have problems with their skin and other parts of their bodies. Prognosis Scleroderma is a chronic disease. This means it may last for months, years, or for a lifetime. There is no cure for it, but it can be treated. With early detection and proper management, many people with scleroderma can lead full, productive lives. Incidence and risk factors Scleroderma is a rare disease. It affects women two to three times more often than men. The disease usually starts between ages 30 and 50. It is sometimes seen in children and the elderly. Causes The cause of scleroderma is unknown. It is not contagious, so you can't catch it from someone or give it to anyone. It is not inherited or passed on from one generation to the next, except in rare instances.

88. HOME Page For SF-TBC Race Logo. FRIENDS FOR scleroderma RUN. Inactive at this time. http://www.scleroderma-texas.org/

SF TEXAS BLUEBONNET CHAPTER Local Activities WHAT ACTIVITY DO YOU WANT TO VISIT TODAY? CHAPTER HOME SITE TEXAS ( PATIENT ADVOCACY NETWORK

89. DermPath scleroderma. Sclerotic lesions, smooth and shiny; Localized forms(morphea, linear scleroderma) and generalized form (progressive http://www.pathology.iupui.edu/drhood/scleroderma.html

Scleroderma Sclerotic lesions, smooth and shiny Localized forms (morphea, linear scleroderma) and generalized form (progressive systemic scleroderma with multi organ involvement) exist Histology: Thickened reticular dermis with entrapment of adnexal structures Return to Dermatopathology Index

90. LEARNING ABOUT SCLERODERMA LEARNING ABOUT scleroderma scleroderma Foundation of Victoria. scleroderma, alsoknown as systematic sclerosis, is an uncommon but not rare disorder. http://www.nevdgp.org.au/geninf/std_misc/LEARNING_ABOUT_SCLERODERMA.htm

LEARNING ABOUT SCLERODERMA Scleroderma Foundation of Victoria. www.vicnet.net.au/~sclerofv/ Scleroderma, also known as systematic sclerosis, is an uncommon but not rare disorder. Many patients, when told they have this problem, find it difficult to find further information on this condition. In particular, it is common for scleroderma to be portrayed "in the wrong light" without an understanding of the type of scleroderma that they have, and also the extent of the condition in their particular case. This information is extremely important as it provides the patient with an understanding of their outlook - what the disease on average might do to the patient and how the disease will affect their future. An appropriate understanding of scleroderma, especially the way it affects the individual with the problem, is the first pre-requisite for gaining self management skills. The management of any chronic illness requires an interaction between the patient, their doctor, other health professionals and their family and friends. Even in the recent past, scleroderma was regarded as a disease with the potential to cause considerable disability, and one that might even cause death. However, the perspective on scleroderma has changed considerably. It is now recognised that it is far more common than it was believed to be, and milder form manifest in many people who never develop more serious disease. Furthermore, whilst a cure is not yet available, a large number of treatment options are now available for the various manifestations of the condition. There is no doubt that the outlook for someone with scleroderma diagnosed nowadays is considerably better than ever before.

91. Scleroderma / Systemic Sclerosis By Drdoc On-line scleroderma / Systemic sclerosis, by drdoc online. abnormal nailfoldcapillaries. The clinical features Of scleroderma. The main clinical http://www.arthritis.co.za/scleroderma.htm

Scleroderma / Systemic sclerosis by drdoc on-line Table of contents Definition and Epidemiology Musculoskeletal involvement in Scleroderma Classification Renal disease in Scleroderma ... Go to Arthritis index page Systemic sclerosis is a generalized disorder of connective tissue, leading to progressive tissue fibrosis. The condition characterized by fibrosis of the skin, but with involvement also of joints, tendons, muscles, and internal organs The condition was first described by Curzio in the 1753. Initially it was seen as a condition affecting the Skin but in 1945, Goetz proposed a description of progressive systemic sclerosis. He described visceral lesions in autopsy cases, whilst studying Medicine and forensic pathology at the University of Cape Town, South Africa. In addition, a limited Scleroderma was described in 1964 by Winterbauer. He referred to a syndrome with calcinosis raynauds phenomenon esophageal dysmotility sclerodactyly , and Telangiectasia . This subsequently became known as the C R E S T syndrome.

92. OBGYN.net - Scleroderma & Pregnancy - A. Iqbal, MD return scleroderma Pregnancy by Asim Iqbal, MD Department of Obstetrics Gynecology Nishtar Hospital, Multan, Pakistan. scleroderma http://www.obgyn.net/displayppt.asp?page=/english/pubs/features/presentations/iq

93. HJD | Department Of Rheumatology Fibromyalgia Lyme Disease Paget's Disease Bursitis Tendonitis Back NeckPain Pain Management New Medications Studies Department Home, scleroderma. http://hjd-www.med.nyu.edu/Rheumatology/sclerod.html

MM_preloadImages('images/nav_osteoon.gif'); MM_preloadImages('images/nav_painon.gif'); MM_preloadImages('images/nav_backneckon.gif'); MM_preloadImages('images/nav_bursitisoff.gif'); MM_preloadImages('images/nav_pagetoff.gif'); MM_preloadImages('images/nav_lymeoff.gif'); MM_preloadImages('images/nav_fibroon.gif'); MM_preloadImages('images/nav_autoimmuneon.gif'); MM_preloadImages('images/nav_jarthritison.gif'); MM_preloadImages('images/nav_arthritison.gif'); Lupus Scleroderma Sjogrens Syndrome Rheumatoid Arthritis Scleroderma

94. Localized Scleroderma Morphea scleroderma means hard skin and is pronounced sklero-derma. sclerodermais a disease that causes fibrosis (hardening) of the skin http://www.skinsite.com/info_scleroderma_localized.htm

Localized Scleroderma I. Definition: Scleroderma means "hard skin" and is pronounced skler-o-derma. Scleroderma is a disease that causes fibrosis (hardening) of the skin and sometimes the internal organs. Scleroderma can range from a form localized to the skin to a severe disease the effects the internal organs known as systemic scleroderma. Localized scleroderma can range from just a few spots on the skin to covering almost the entire skin surface. The skin lesions of localized scleroderma feel firm and hard. The color is ivory to yellowish in color. The skin lesions of localized scleroderma are usually seen on the trunk but can also occur on the face, arms, and legs. Localized scleroderma may last for a few months to many years. The condition is four times more common in women and usually starts between the ages of twenty and fifty. II. Cause: The cause of scleroderma is unknown. III. Treatment: There is not a known medication that will stop or reverse the process of scleroderma. Milder forms of scleroderma may be helped by topical cortisone medications or cortisone injections.

95. The Contact A Family Directory - SCLERODERMA printer friendly, scleroderma, Rheumatologist, Royal Free Hospital, London,UK. scleroderma SOCIETY. scleroderma Society 3 Caple Rd London NW10 http://www.cafamily.org.uk/Direct/s18.html

printer friendly SCLERODERMA home more about us in your area conditions information ... how you can help search this site Scleroderma (hard skin) is a little-known disease of the connective tissue, immune system and blood vessels which primarily affects women in the child-bearing years, though it can affect anyone of any age. It results in taut, hard, discoloured skin and may also affect the internal organs. Scleroderma is divided into localised forms (morphoea, linear scleroderma) and generalised scleroderma (systemic sclerosis, SSc). SSc has a severe form with patients having wide spread skin involvement and a mild form with patients having skin involvement only in the hands, lower arms, feet, lower legs and face. The severe form, diffuse cutaneous SSc, affects 40% of sufferers; the mild form, limited cutaneous SSc, 60%. In the severe form, wide areas of the skin are affected and internal organ involvement occurs early. Scleroderma can be fatal, with lung disease as the chief cause of death. Survivors may have a reduced quality of life with breathlessness, kidney disease, heart disease, digestive problems and reduced function in joints, muscles and hands. In the mild form, there is limited skin involvement with the later development of gut disease (and thus difficulty in swallowing and eating) and lung problems, usually pulmonary hypertension. Additionally there may be calcinosis (deposits of calcium which mass under the skin and protrude), dry eyes and mouth, ulceration and a very poor circulation.

96. Page 43 Home scleroderma. scleroderma is a chronic autoimmune disease that involves theskin and connective tissue. There are two types, localized and systemic. http://www.aarda.org/page43.html

Scleroderma Scleroderma is a chronic autoimmune disease that involves the skin and connective tissue. There are two types, localized and systemic. In the localized type, the skin shows one or more patches of sclerosis (thickening and hardening). The systemic type involves the skin and the connective tissue. This article deals with the systemic forms of scleroderma. Systemic forms of scleroderma include progressive systemic sclerosis (PSS), also known as systemic sclerosis (SS), and the CREST syndrome. Systemic scleroderma involves body systems such as the esophagus, intestines, lungs, heart and kidneys. Diffuse scleroderma is a term which describes systemic sclerosis and skin changes on many parts of the body. Tight, glossy skin may be present on the trunk and upper arms as well as on the face, chest and extremities. The CREST syndrome is an acronym made up of the first letters of the five most prominent manifestations of this form of scleroderma. They are: calcinosis (accumulation of calcium salts under the skin), Raynaud's phenomenon, esophageal dysfunction, sclerodactyly and telangiectasia. Systemic scleroderma can occur in both men and women, and it typically affects women in their thirties and forties. Each case is different, and the severity of the disease varies among patients. For more information on scleroderma or other autoimmune disorders, please click on the request information icon below.

97. LookSmart - Scleroderma Search the Web for. LookSmart Home. Featured Sponsors. scleroderma. 1UpHealth scleroderma Know its causes, diagnosis, and treatment. http://www.looksmart.com/eus1/eus302562/eus317837/eus317920/eus53948/eus273036/e

98. Scleroderma scleroderma,, Print this article, scleroderma has frequently been difficult todifferentiate from other disorders associated with induration of the skin. http://www.amershamhealth.com/medcyclopaedia/Volume III 1/scleroderma.html

Medcyclopaedia About Medcyclopaedia Back to Amersham Health Medical Professional site Search for: Type a word or a phrase. All forms of the word are searchable. Browse entry words starting with: A B C D ... Other characters Try our Medcyclopaedia Premium Edition with added tools and functionality tailored to make your working day easier. The following tools are presently available: Expanded search Advanced search Anatomical images with and without annotations For Medical Professionals only, registration required Scleroderma, also called progressive systemic sclerosis, a generalized disorder of connective tissue of unknown cause that affects principally the skin, lungs, gastrointestinal tract, heart, kidneys and musculoskeletal system. Another name for this disease is progressive systemic sclerosis. Severe fibrosis and alterations of small blood vessels are among its pathologic features. Many of the diverse clinical manifestations in this disease are represented on radiographs as atrophy and calcification of soft tissue and bone resorption. Frequently the abnormalities predominate in the phalanges of the hand, although diffuse subcutaneous calcification, widespread periarticular calcification, and bone resorption are encountered at other sites, such as the mandible, the ribs and the clavicles. Joint alterations include erosive arthritis and intra-articular calcific collections. Scleroderma has frequently been difficult to differentiate from other disorders associated with induration of the skin. Among the conditions with similar features are

99. Scleroderma scleroderma. scleroderma can be divided into those with limited skininvolvement or those with more generalized skin involvement. http://www.hjd.org/hospitals/hjd/html/body_scleroderma.html

Arthritis Juvenile Arthritis Autoimmmune Diseases Lupus ... Clinical Immunology Lab Scleroderma Scleroderma is a connective tissue disease, the origin of which is unknown, characterized by fibrosis, or thickening by scar tissue, of the skin and sometimes internal organs. Since many of the patients have autoantibodies in the blood it is considered an autoimmune disorder. Almost all patients with scleroderma have Raynauds phenomenon and with exposure to cold temperature their fingers and sometimes toes become painful and turn first white, then blue and red. Scleroderma can be divided into those with limited skin involvement or those with more generalized skin involvement. Limited skin disease can be accompanied by additional features including skin Calcinosis, Raynauds phenomenon, abnormalities of the Esophagus (food pipe), Sclerodactyly (tightening of skin on the fingers) and skin Telangiectasias (spider veins). This type of scleroderma is referred to as CREST syndrome. Patients with diffuse, generalized skin fibrosis may have the type of sclerodenna known as systemic sclerosis and may develop fibrosis involving the lungs, heart, gastrointestinal tract and kidneys.

100. Sclero The scleroderma Center at Boston University School of Medicine and Boston MedicalCenter is a multidisciplinary effort encompassing basic and clinical research http://medicine.bu.edu/sc/sclero.htm

Joseph H. Korn, MD, Director Robert Simms, MD, Associate Director, Clinical Programs Peter Merkel MD, Clinical Trials Kate Schrade, Admin. Asst. Clinical Programs Tina Elias-Todd, MD Fellow Harrison Farber MD, Pulmonary Eugene Kissin, MD, Fellow Dennis Liu, MD Fellow Arthur Theodore MD, Pulmonary Basic Research Programs Allesandra Farina, MD Robert Lafyatis, MD Raphael Lemaire, Ph.D. Lauren Kim, MD Fellow Tako Ogawa, MD David Strehlow, PhD Russell Widom, PhD The Scleroderma Center at Boston University School of Medicine and Boston Medical Center is a multidisciplinary effort encompassing basic and clinical research, clinical trials and patient care. The Scleroderma Center is part of the Boston University Arthritis Center, which has an extensive research program in immunology, molecular and cell biology, biochemistry and epidemiology. Clinical care is provided at the Boston Medical Center, including clinical trials at the NIH-funded Clinical Research Center of Boston University Medical Center. Research is supported by grants from the NIH, Arthritis Foundation, Scleroderma Research Fund, and kind gifts from patients and corporate donors. The support we receive allows us to provide a broad range of clinical and advisory services to patients with scleroderma and other autoimmune diseases. Clinical Programs Over the last 9 years, approximately 800 patients with scleroderma have been evaluated, including patients from Southeast Asia, South America, the Middle East and various parts of the U.S. Special programs for the evaluation of lung disease and pulmonary hypertension are in place. Our program is part of the international Scleroderma Clinical Trials Consortium, a group that conducts multicenter trials of therapies in scleroderma. We currently have two studies for skin disease in early scleroderma, anti-body to TGFß and interferon ß-1.

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