61. Craniosynostosis - Lucile Packard Children's Hospital Craniofacial Anomalies. craniosynostosis What is craniosynostosis?The normal What causes craniosynostosis? craniosynostosis occurs http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/craniofacial/cranio.html

Craniofacial Anomalies Ear, Nose, and Throat (ENT) Oral and Maxillofacial Surgery Plastic Surgery Clinic ... Dental and Oral Health Craniofacial Anomalies Craniosynostosis What is craniosynostosis? The normal skull consists of several plates of bone that are separated by sutures. The sutures (fibrous joints) are found between the bony plates in the head. As the infant grows and develops, the sutures close, forming a solid piece of bone, called the skull. Craniosynostosis is a condition in which the sutures close too early, causing problems with normal brain and skull growth. Premature closure of the sutures may also cause the pressure inside of the head to increase and the skull or facial bones to change from a normal, symmetrical appearance. What causes craniosynostosis? Craniosynostosis occurs in one out of 2,000 live births and affects males twice as often as females. Craniosynostosis is most often sporadic (occurs by chance). In some families, craniosynostosis is inherited in one of two ways: autosomal recessive Autosomal recessive means that two copies of the gene are necessary to express the condition, one inherited from each parent, who are carriers. Carrier parents have a one in four, or 25 percent, chance with each pregnancy, to have a child with craniosynostosis. Males and females are equally affected.

62. Craniosynostosis - Lucile Packard Children's Hospital Neurological Disorders. craniosynostosis What is craniosynostosis?The normal What causes craniosynostosis? craniosynostosis occurs http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/neuro/cranio.html

Electroencephalography (EEG) Laboratory Motion and Gait Analysis Laboratory Movement Disorders Neurology ... Neurological Disorders Neurological Disorders Craniosynostosis What is craniosynostosis? The normal skull consists of several plates of bone that are separated by sutures. The sutures (fibrous joints) are found between the bony plates in the head. As the infant grows and develops, the sutures close, forming a solid piece of bone, called the skull. Craniosynostosis is a condition in which the sutures close too early, causing problems with normal brain and skull growth. Premature closure of the sutures may also cause the pressure inside of the head to increase and the skull or facial bones to change from a normal, symmetrical appearance. What causes craniosynostosis? Craniosynostosis occurs in one out of 2,000 live births and affects males twice as often as females. Craniosynostosis is most often sporadic (occurs by chance). In some families, craniosynostosis is inherited in one of two ways: autosomal recessive Autosomal recessive means that two copies of the gene are necessary to express the condition, one inherited from each parent, who are obligate carriers. Carrier parents have a one in four, or 25 percent, chance with each pregnancy, to have a child with craniosynostosis. Males and females are equally affected.

63. Craniosynostosis craniosynostosis. Some forms of craniosynostosis are associated with syndromesof multiple congenital (cranial and noncranial) anomalies. http://uscneurosurgery.com/glossary/c/craniosynostosis.htm

Craniosynostosis Premature fusion of the sutures of the skull. Some forms of craniosynostosis are associated with syndromes of multiple congenital (cranial and non-cranial) anomalies. The most obvious complication is cosmetic: babies (and adults) with abnormally-shaped skulls look different and, to many people, "funny", "ugly", or worse. A skull that does not enlarge over the enlarging brain during the first months and years of life may prevent the brain from growing to its full size and the patient from achieving his or her intellectual potential. As the volume of brain tissue increases it eventually completely fills the space inside the skull and starts to push out against it which causes the pressure inside the skull (intracranial pressure) to increase. Increased intracranial pressure inhibits normal brain growth and development and can interfere with blood flow to the brain which could result brain damage. Papilledema with optic nerve injury can occur.

64. Radiology Reports Craniosynostosis Diagnostic reports. NEURORADIOLOGY. craniosynostosis. Radiologist's report. craniosynostosisIn McCarthy, Pastic surgery vol. 4 Phila, WB Saunders 19903017), http://uscneurosurgery.com/patient education/reports/diagnostic/radiology/crania

Neuroradiology Diagnostic reports NEURORADIOLOGY Craniosynostosis Radiologist's report figure: baby with plagiocephaly due to unilateral coronal synostosis (McCarthy, et al. Craniosynostosis In: McCarthy, Pastic surgery vol. 4 Phila, WB Saunders 1990:3017) Description of Craniosynostectomy Risks and Complications of Craniosynostectomy Clinical Presentation of Craniosynostosis Pathophysiology of Craniosynostosis ... Diagnostic workup of Craniosynostosis Pediatric Specialty Center Return to uscneurosurgery.com Homepage

65. Children's Health At Doernbecher - Child Health A-Z craniosynostosis, RELATED SERVICES. ·, Cleft Palate/Craniofacial. What is craniosynostosis?The normal skull consists http://www.ohsuhealth.com/dch/health/craniofacial/cranio.asp

Craniofacial Anomalies Index Anatomy of the Newborn Skull Overview of Craniofacial Anomalies The Craniofacial Team ... Online Resources You have selected the following Health topic: - Adolescent Medicine - Burns - Cardiovascular Disorders - Care of the Terminally Ill Child - Children Having Surgery - Common Childhood Injuries and Poisoning - Craniofacial Anomalies - Dermatology - Diabetes - Eye Care - Genetics - Growth and Development - High-Risk Newborn - High-Risk Pregnancy - Immunizations - Infectious Diseases - Mental Health - Neurological Disorders - Normal Newborn - Oncology - Orthopaedics - The Pediatrician - Pregnancy and Childbirth - Respiratory Disorders - Transplantations - Well-Care Visits Craniosynostosis RELATED SERVICES Cleft Palate/Craniofacial What is craniosynostosis? The normal skull consists of several plates of bone that are separated by sutures. The sutures (fibrous joints) are found between the bony plates in the head. As the infant grows and develops, the sutures close, forming a solid piece of bone, called the skull. Craniosynostosis is a condition in which the sutures close too early, causing problems with normal brain and skull growth. Premature closure of the sutures may also cause the pressure inside of the head to increase and the skull or facial bones to change from a normal, symmetrical appearance.

66. OHSU Doernbecher - Neurological Disorders craniosynostosis, What is craniosynostosis? The normal skull consists of severalplates of bone that are separated by sutures. What causes craniosynostosis? http://www.ohsuhealth.com/dch/health/neuro/congen_cran.asp

Neurological Disorders Home Overview of Nervous System Disorders Anatomy of the Brain Diagnostic Tests ... Chiari Malformation Craniosynostosis Hydrocephalus Microcephaly Spina Bifida Neurological Disorders in the Newborn ... Online Resources You have selected the following Health topic: - Adolescent Medicine - Burns - Cardiovascular Disorders - Care of the Terminally Ill Child - Children Having Surgery - Common Childhood Injuries and Poisoning - Craniofacial Anomalies - Dermatology - Diabetes - Eye Care - Genetics - Growth and Development - High-Risk Newborn - High-Risk Pregnancy - Immunizations - Infectious Diseases - Mental Health - Neurological Disorders - Normal Newborn - Oncology - Orthopaedics - The Pediatrician - Pregnancy and Childbirth - Respiratory Disorders - Transplantations - Well-Care Visits Craniosynostosis RELATED SERVICES Cleft Palate/Craniofacial Neonatal Medicine Neurological Surgery What is craniosynostosis? The normal skull consists of several plates of bone that are separated by sutures. The sutures (fibrous joints) are found between the bony plates in the head. As the infant grows and develops, the sutures close, forming a solid piece of bone, called the skull. Craniosynostosis is a condition in which the sutures close too early, causing problems with normal brain and skull growth. Premature closure of the sutures may also cause the pressure inside of the head to increase and the skull or facial bones to change from a normal, symmetrical appearance.

67. CCDD: Craniosynostosis The Center for Craniofacial Development and Disorders (CCDD), at Johns HopkinsUniversity, has a comprehensive list of craniosynostosis links and articles. http://www.hopkinsmedicine.org/craniofacial/Gateway/Craniosynostosis.cfm

Site Map About Us Family Physician ... Feedback Home About Us Family Physician Scientist ... Feedback Questions: CCDD Site Issues: Webmaster Craniosynostosis A variety of conditions in which the bones of the skull join together too early, affecting the development and shape of the skull. Craniosynostosis may occur alone or as part of a genetic syndrome. Visit these Craniosynostosis links to learn more: About Us: Craniosynostosis Brochure - Craniosynostosis is defined as the premature closing of one or more of the spaces that are normally present between individual bones of the skull. Infants born with abnormal skull shapes should be evaluated for craniosynostosis. Some abnormal skull shapes at birth may be related to fetal head position and not premature fusion of sutures; this type of deformity will usually correct itself in several months. Family: Joan Richtsmeier Shares Her Story - In the case of craniosynostosis involving the sagittal suture, the brain compensates for its inability to expand upward by growing more toward the front and back, elongating the forehead and the back of the head.

68. CCDD: Family: Patient Care: Descriptions Of Disorders: Craniosynostosis Incidence craniosynostosis occurs approximately 1 in 3000 births. The most obviousmanifestations of craniosynostosis is an alteration of head shape. http://www.hopkinsmedicine.org/craniofacial/PatientCare/Article.cfm?ArticleID=64

69. Craniosynostosis : Meddie Health Search (Rating 0.00 Votes 0) Rate It. Craniosupport Support, information,and research tools to parents of children with craniosynostosis. http://www.meddie.com/search/Health/Consumer_Support_Groups/Facial_Differences/C

HOME ADD A LINK MODIFY A LINK NEW LINKS ... TOP RATED Search Meddie: the entire directory only this category More search options Home Health Consumer Support Groups ... Facial Differences : Craniosynostosis ITEMS: LINKS: Asher's CS An individual's struggle with CS, contains information and links. (Rating: 0.00 Votes: 0) Rate It Craniosupport Support, information, and research tools to parents of children with craniosynostosis. (Rating: 0.00 Votes: 0) Rate It Craniosynostosis and Parents' Support Site dedicated to giving families dealing with craniosynostosis support and information. (Rating: 0.00 Votes: 0) Rate It Parents of Children with Craniosynostosis (PCC) A site offering information and support about craniosynostosis. For families in Eastern Idaho and parts of Utah. (Rating: 0.00 Votes: 0) Rate It HOME ADD A LINK MODIFY A LINK ... Design © ISC Enterprises Inc.

70. Craniosynostosis craniosynostosis is a congenital anomaly characterized by premature closureof the fibrous joints between the bones of the skull. craniosynostosis. http://healthlink.mcw.edu/article/921395195.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Neurology By keywords: Receive Health Link via email! Subscribe now >> Craniosynostosis Craniosynostosis is a congenital anomaly characterized by premature closure before the completion of brain growth of one or more cranial sutures (the fibrous joints between the bones of the skull). The disorder results in an abnormal skull and head shape. The condition may be a feature of a chromosomal or genetic syndrome or abnormality, or it may occur spontaneously. Some cases may be associated with disorders such as microcephaly (abnormally small head) and hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain). The first sign is an abnormal head shape. Other symptoms, which include increased intracranial pressure, developmental delay, and mental retardation, may be caused by constriction of the growing brain. Seizures and blindness may also occur. Treatment for craniosynostosis generally consists of surgery (usually performed early in life) to relieve increased intracranial pressure, assure capacity of the skull to accommodate brain growth, and improve the appearance of the head.

71. Virtual Children's Hospital: Paediapaedia: Craniosynostosis Paediapaedia Neurological Diseases craniosynostosis. Plain films detect89% of craniosynostosis while CT detects 94% of craniosynostosis. http://www.vh.org/pediatric/provider/radiology/PAP/NeuroDiseases/Craniosyns.html

Paediapaedia: Neurological Diseases Craniosynostosis Michael P. D'Alessandro, M.D. Peer Review Status: Internally Peer Reviewed Clinical Presentation: Irregularly shaped skull. Etiology/Pathophysiology: Is premature closure of a suture. Can be either primary (idiopathic) or secondary (due to skeletal dysplasias and syndromes, metabolic disease, hematologic disorders, ventricular shunting, and miscellaneous malformations). The primary ones develop in utero and are apparent at birth or shortly thereafter. There is a 3:1 male predominance. Pathology: Not applicable Imaging Findings: The skull is altered in shape. The involved suture may appear narrowed, demonstrate parasutural sclerosis, sharpening and straightening of the sutural edges, and development of bony bridges. There may be partial or complete fusion of a suture, but a short segment of synostosis often produces the same deformity as a complete fusion. Multiple sutures are involved 11% of time. Plain films detect 89% of craniosynostosis while CT detects 94% of craniosynostosis. Sagittal craniosynostosis (dolichocephaly, scaphocephaly) accounts for 56% of cases and has an elongated cranial vault.

72. The DRM WebWatcher: Craniosynostosis A Disability Resources Monthly guide to the best online resourcesabout craniosynostosis and related conditions. http://www.disabilityresources.org/CRANIO.html

Home Subjects States Librarians ... Contact Us The DRM WebWatcher Craniosynostosis Updated 4/26/2001 A B C D ... About/Hint/Link Craniosynostosis is a congenital anomaly characterized by premature closure of one or more cranial sutures before the completion of brain growth. These websites provide more information. Craniosynostosis This fact sheet from the National Institute of Neurological Disorders and Stroke provides basic information about craniosynostosis, including treatment, prognosis, research, and resources. Craniosynostosis This fact sheet from the American Association of Neurological Surgeons / Congress of Neurological Surgeons provides an overview of the disorder, frequently asked questions, and other resources. Craniosynostosis A fact sheet with a focus on surgery from the Children's Medical Center of Dallas. Craniosynostosis and Positional Plagiocephaly Support This is the website of a nonprofit organization dedicated to offering support and providing information to families who have a child with craniosynostosis and positional plagiocephaly. It includes basic information about the two disorders, printable flyers, a list of doctors, links, an active message board, and more, as well as information about the organization's services. Related Subjects Facial Differences Resources in your state (c) 1997-2001 Disability Resources, inc.

73. MEDLINEplus Medical Encyclopedia: Craniosynostosis craniosynostosis. The cause of craniosynostosis is for the most part unknown.craniosynostosis can also occur with some inherited disorders. http://www.nlm.nih.gov/medlineplus/ency/article/001590.htm

Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Craniosynostosis Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Skull of a newborn Alternative names Return to top Premature closure of sutures Definition Return to top The early closure of the bony sutures in an infant's head, preventing further growth of the skull. Causes, incidence, and risk factors Return to top The cause of craniosynostosis is for the most part unknown. Craniosynostosis can also occur with some inherited disorders. In a normal infant's head, the sutures mark the boundaries between the bony plates that make up the skull. Premature closure of sutures stops bony growth and results in deformity of the skull. The shape of the deformity is determined by which sutures are involved. If the sagittal suture (the suture running from the front to back of the head) closes, the head develops a long, narrow appearance. If one of the coronal sutures (running across the top of the head roughly from ear to ear) closes, it results in severe deformity of the head and may affect the appearance of the face and cause visual abnormalities. Closure of the sagittal suture is more common in boys. Closure of the coronal suture is often associated with genetic syndromes.

74. CMGS-Craniosynostosis/13.1.00 craniosynostosis. craniosynostosis is caused by the premature fusion of oneor more cranial sutures, preventing further growth along the suture. http://www.ich.ucl.ac.uk/cmgs/cranio99.htm

Craniosynostosis Craniosynostosis is caused by the premature fusion of one or more cranial sutures, preventing further growth along the suture. Excessive growth at other sutures to compensate for this leads to an abnormal head shape. It affects approximately 1 in 2500 individuals, and may be caused by genetic or environmental factors. It is a factor in over 100 described syndromes, most of the common syndromes are dominantly inherited, and in most syndromes the craniosynostosis is accompanied by limb abnormalities suggesting that aspects of craniofacial development share common molecular pathways. The abnormal skull growth may be associated with increased intracranial pressure, impaired cerebral blood flow, airway obstruction, impaired vision and hearing and learning difficulties. Therefore, it can cause significant problems despite advances in surgical management. The FGFRs Mutations have been described in craniosynostosis syndromes in FGFR1, 2 and 3 but not FGFR4. Mutations in craniosynostosis syndromes have also been reported in two other genes, MSX2 and TWIST. A single family has been shown to have Boston craniosynostosis as a result of an MSX2 mutation, and Saethre-Chotzen syndrome has been shown to result from mutations in TWIST. TWIST The TWIST gene encodes a transcription factor with a helix-loop-helix domain. Twist genes have been characterised in mouse, human

75. Craniofacial Anomalies - Craniosynostosis craniosynostosis. What is craniosynostosis? The normal skull consists of severalplates of bone that are separated by sutures. What causes craniosynostosis? http://www.musckids.com/health_library/craniofacial/cranio.htm

Home About Us Departments MUSC eNurse ... Your Hospital Visit 171 Ashley Ave. Charleston, SC 29425 800-424-MUSC Print Version Craniofacial Anomalies Craniosynostosis What is craniosynostosis? The normal skull consists of several plates of bone that are separated by sutures. The sutures (fibrous joints) are found between the bony plates in the head. As the infant grows and develops, the sutures close, forming a solid piece of bone, called the skull. Craniosynostosis is a condition in which the sutures close too early, causing problems with normal brain and skull growth. Premature closure of the sutures may also cause the pressure inside of the head to increase and the skull or facial bones to change from a normal, symmetrical appearance. What causes craniosynostosis? Craniosynostosis occurs in one out of 2,000 live births and affects males twice as often as females. Craniosynostosis is most often sporadic (occurs by chance). In some families, craniosynostosis is inherited in one of two ways: autosomal recessive Autosomal recessive means that two copies of the gene are necessary to express the condition, one inherited from each parent, who are carriers. Carrier parents have a one in four, or 25 percent, chance with each pregnancy, to have a child with craniosynostosis. Males and females are equally affected.

76. 1Up Health > Craniosynostosis > Causes, Incidence, And Risk Factors Of Craniosyn Comprehesive information on craniosynostosis (Premature closure of sutures). craniosynostosisCauses, Incidence, and Risk Factors. Alternative names http://www.1uphealth.com/health/craniosynostosis_info.html

1Up Health Craniosynostosis Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Craniosynostosis Information Craniosynostosis Causes, Incidence, and Risk Factors Alternative names : Premature closure of sutures Definition : The early closure of the bony sutures in an infant's head, preventing further growth of the skull. Causes, Incidence, and Risk Factors The cause of craniosynostosis is for the most part unknown. Craniosynostosis can also occur with some inherited disorders. In a normal infant's head, the sutures mark the boundaries between the bony plates that make up the skull. Premature closure of sutures stops bony growth and results in deformity of the skull. The shape of the deformity is determined by which sutures are involved. If the sagittal suture (the suture running from the front to back of the head) closes, the head develops a long, narrow appearance. If one of the coronal sutures (running across the top of the head roughly from ear to ear) closes, it results in severe deformity of the head and may affect the appearance of the face and cause visual abnormalities. Closure of the sagittal suture is more common in boys. Closure of the coronal suture is often associated with genetic syndromes.

77. Washington University: Pediatric Neurosurgery / Clinical Programs: Craniosynosto Pediatric Neurosurgery Clinical Programs craniosynostosis Clinic Duringthe first few years of life, the child's head is growing and changing. http://pedns.wustl.edu/cranioclinic.htm

Clinical Programs : Craniosynostosis Clinic During the first few years of life, the child's head is growing and changing. The skull, composed of the thin bones of the vault and the thicker bones at the cranial base, are adapting and accomodating the developing and expanding brain. This growth is quite rapid during the first 18 months of life, and continues for some years more. The growth and shape of the skull can be affected by many factors - some externally applied, some the result of problems with the brain, and some the result of direct abnormalities of the skull's development. The Department of Pediatric Neurosurgery is actively involved in the evaluation and treatment of the various abnormalities of skull growth and shape. These problems are diagnosed with a combination of clinical evaluation and radiographic imaging techniques . Many of the misshapen heads seen by our department are the result of positional plagiocephaly (deformation), and do not require surgical treatment. We have experienced orthotists available to assist in the molding helmet correction of these problems without surgery. If surgery is required, the members of the department are skilled in the various surgical techniques used for remodeling and reconstruction of the skull. Even the most complex cranio-facial surgeries are routinely undertaken, taking advantage of our experienced surgical and post-surgical teams, including the pediatric neuro-anesthesiologists and pediatric intensive care unit staff. Our surgeons work in conjunction with the plastic surgeons of the St. Louis Children's Hospital Craniofacial Team on cases of severe malformations of the face and skull and those associated with other syndromes (such as Apert's and Crouzon's syndromes).

78. Craniofacial Anomalies - Craniosynostosis Site Search. Find A Doctor. For a doctor who specializes in this topic, click here.craniosynostosis. What is craniosynostosis? What causes craniosynostosis? http://www.chkd.org/Craniofacial/cranio_jh.asp

More Health Information Adolescent Medicine Allergy/Immunology Anesthesiology Arthritis Burns Cardiology Craniofacial Dental Medicine Dermatology Developmental Peds Diabetes Digestive Ear, Nose, Throat Genetics Gastroenterology Growth Hematology High Risk Newborn High Risk Pregnancy Infectious Disease Mental Health Neonatology Nephrology Neurology Normal Newborn Normal Pregnancy Oncology Ophthalmalogy Orthopaedics Otolaryngology Pediatric Intensive Care Pediatric Surgery Pediatrics Physical Medicine Plastic Surgery Respiratory/Pulmonology Rheumatology Safety Surgery Terminal Transplant Urology Site Search For a doctor who specializes in this topic, click here. Craniosynostosis What is craniosynostosis? The normal skull consists of several plates of bone that are separated by sutures.The sutures (fibrous joints) are found between the bony plates in the head. As the infant grows and develops, the sutures close, forming a solid piece of bone, called the skull. Craniosynostosis is a condition in which the sutures close too early, causing problems with normal brain and skull growth. Premature closure of the sutures may also cause the pressure inside of the head to increase and the skull or facial bones to change from a normal, symmetrical appearance. What causes craniosynostosis?

79. CRANIOSYNOSTOSIS-BRACHYDACTYLY Features Listed For craniosynostosisBRACHYDACTYLY. McKusick craniosynostosis; Hypertelorism;Hypoplastic maxilla (excluding malar region); Hypoplastic phalanges; http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?2608

80. CRANIOSYNOSTOSIS, ADELAIDE TYPE Features Listed For craniosynostosis, ADELAIDE TYPE. McKusick Stature/length short,proportionate; Acrocephaly/turricephaly; Microcephaly; craniosynostosis; http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?6078

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